Evidence map›Paper›PMID 27932325›Full record

ArticleBlood2016

Twisting IL-1 signaling to kill CML stem cells.

Lorenzo Stramucci, Danilo Perrotti

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Blood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lorenzo StramucciUNIVERSITY OF MARYLAND SCHOOL OF MEDICINE.
Danilo PerrottiUNIVERSITY OF MARYLAND SCHOOL OF MEDICINE.ORCID 0000-0003-0726-8766

Funding

Role of microRNAs in the regulation of CML stem cell survival and self renewalR01CA163800 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI PERROTTI, DANILO · 2012 to 2017
$1.6M
Role of SETBP1 in adult Ph+ acute lymphoblastic leukemiaR21CA209183 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI PERROTTI, DANILO · 2016 to 2017
$369k
NCI NIH HHS R01 CA163800NCI NIH HHS R21 CA209183
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Interleukin-1Leukemia, Myelogenous, Chronic, BCR-ABL PositiveHumansImatinib MesylateNeoplastic Stem CellsSignal TransductionStem CellsImatinib MesylateInterleukin-1

Identifiers

PMID27932325
OpenAlexW2559836759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.