Evidence map›Paper›PMID 27931684›Full record

ArticleInternational journal of mycobacteriology2016

Inhibition of apoptosis by Rv2456c through Nuclear factor-κB extends the survival of Mycobacterium tuberculosis.

Kristen L Jurcic Smith, Sunhee Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of mycobacteriology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Research progress in PANoptosis mechanisms and their interplay with tuberculosis.Frontiers in cellular and infection microbiology · 2026
    Review
  3. Review
  4. Intracellular behavior ofFrontiers in cellular and infection microbiology · 2023
    Article
  5. Different modalities of host cell death and their impact onAmerican journal of physiology. Cell physiology · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kristen L Jurcic SmithHuman Vaccine Institute, Duke University School of Medicine, Durham, NC, USA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Sunhee LeeHuman Vaccine Institute, Duke University School of Medicine, Durham, NC, USA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA; Department of Pathology, Duke University School of Medicine, Durham, NC, USA. Electronic address: Sunhee.lee@duke.edu.

Funding

Effects of mycobacterial infections induced cell death on host immune responseR21AI090434 · NIAID · DUKE UNIVERSITY · PI LEE, SUNHEE · 2011 to 2012
$432k
NIAID NIH HHS R21 AI090434
6 · The paper itself

Abstract

Mycobacterium tuberculosis, the causative agent of tuberculosis, is an intracellular pathogen with several survival mechanisms aimed at subverting the host immune system. Apoptosis has been shown to be mycobactericidal, to activate CD8

Indexed as

ApoptosisHost-Pathogen InteractionsImmunity, InnateMicrobial ViabilityAnimalsApoptosis Regulatory ProteinsBacterial ProteinsCell LineDisease Models, AnimalDNA Transposable ElementsHumansMice, Inbred C57BLMutagenesis, InsertionalMycobacterium tuberculosisTuberculosisApoptosis Regulatory ProteinsBacterial ProteinsDNA Transposable ElementsApoptosisMycobacterium tuberculosisTuberculosisVaccine

Identifiers

PMID27931684
PMCPMC5975360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.