ArticleBMC pediatrics2016
Prevalence and risk factors for vitamin D insufficiency and deficiency at birth and associated outcome.
Article in BMC pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Maternal Dietary Factors and the Risk of Autism Spectrum Disorders: A Systematic Review of Existing Evidence.Autism research : official journal of the International Society for Autism Research · 2020Pooled it
- Determinants and Measurement of Neonatal Vitamin D: Overestimation of 25(OH)D in Cord Blood Using CLIA Assay Technology.The Journal of clinical endocrinology and metabolism · 2020Trial
- Determining the Relationship Between Maternal and Neonatal Vitamin D Serum Levels in Term Infants With and Without Sepsis.Journal of family & reproductive health · 2025Article
- Prevalence of vitamin D deficiency in exclusively breastfed infants at Charoenkrung Pracharak Hospital.World journal of clinical pediatrics · 2024Article
- Relationship Between the Level of Vitamin D3 Deficiency and Successful Osseointegration: A Prospective Clinical Study.TheScientificWorldJournal · 2024Article
- Observational
- Maternal Vitamin D Levels During Pregnancy in Association With Autism Spectrum Disorders (ASD) or Intellectual Disability (ID) in Offspring; Exploring Non-linear Patterns and Demographic Sub-groups.Autism research : official journal of the International Society for Autism Research · 2020Article
- Screening of vitamin D and calcium concentrations in neonates of mothers at high risk of vitamin D deficiency.BMC pediatrics · 2020Article
- Vitamin D sufficiency in young Brazilian children: associated factors and relationship with vitamin A corrected for inflammatory status.Public health nutrition · 2020Article
- The prevalence and determinants of vitamin D deficiency in Indonesian infants at birth and six months of age.PloS one · 2020Article
- Factors Influencing Vitamin D Levels in Neonatal Umbilical Cord Blood: A Two-Center Study From Tibet and Shenyang.Frontiers in pediatrics · 2020Article
- Comparison of seasonal serum 25-hydroxyvitamin D concentrations among pregnant women in Mongolia and Boston.The Journal of steroid biochemistry and molecular biology · 2019Article
- Newborn vitamin D levels in relation to autism spectrum disorders and intellectual disability: A case-control study in california.Autism research : official journal of the International Society for Autism Research · 2019Article
- Stabilization of Vitamin D in Pea Protein Isolate Nanoemulsions Increases Its Bioefficacy in Rats.Nutrients · 2019Article
- Prevalence of vitamin D deficiency in cord blood of newborns and the association with maternal vitamin D status.European journal of pediatrics · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOccurrence and consequence of cord blood (CB) vitamin D insufficiency/deficiency has not been adequately explored despite rising concern regarding this topic in pediatrics. This study was designed to determine the rate, maternal risk factors, and clinical outcomes in infants in association with vitamin D insufficient/deficient status at birth.
methodsAmerican Academy of Pediatrics (AAP) defined levels (ng/mL) were utilized to categorize the vitamin D status in CB samples as deficient (5-15), insufficient (16-20), and sufficient (21-100). We used descriptive statistics and multiple regression models to identify the rate and factors associated with vitamin D deficiency/insufficiency and related outcomes in the enrolled mother-infant pairs.
resultsThis prospective study was conducted at a single center on postpartum women and their infants. Vitamin D deficiency and insufficiency was recorded in 38.9 and 29.8% respectively of the 265 CB samples. Deficient CB vitamin D levels in infants were associated with maternal Black, Hispanic, or Asian race/ethnicity, younger age, and increased number of pregnancies. The likelihood for infants to be born with an insufficient vitamin D level increases with younger maternal age and the number of pregnancies as well as Asian ethnicity. We did not find an association between the vitamin D status at birth and pre-discharge clinical characteristics of the neonates.
conclusionsThe likelihood for an infant to be born with vitamin D deficiency/insufficiency is relatively high and is related mainly to younger maternal age, gravidity, and non-White race/ethnicity. Our findings raise a question regarding the adequacy of the AAP recommended vitamin D supplementation requirements without knowing the infant's vitamin D status at birth.
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