Evidence map›Paper›PMID 27930881›Full record

ArticleThe journal of physical chemistry. B2017

Ultraslow Domain Motions in HIV-1 TAR RNA Revealed by Solid-State Deuterium NMR.

Wei Huang, Prashant S Emani, Gabriele Varani, Gary P Drobny

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. RNA Dynamics by NMR Spectroscopy.Chembiochem : a European journal of chemical biology · 2019
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wei HuangDepartment of Chemistry, University of Washington , Box 351700, Seattle 98195, United States.
Prashant S EmaniDepartment of Chemistry, University of Washington , Box 351700, Seattle 98195, United States.ORCID 0000-0002-3091-5231
Gabriele VaraniDepartment of Chemistry, University of Washington , Box 351700, Seattle 98195, United States.
Gary P DrobnyDepartment of Chemistry, University of Washington , Box 351700, Seattle 98195, United States.ORCID 0000-0002-7293-1897
University of Washington · US

Funding

Solution and Solid State NMR studies of Conformational Adaptation and Dynamics inR01GM109417 · NIGMS · UNIVERSITY OF WASHINGTON · PI DROBNY, GARY PETER · 2013 to 2016
$1.4M
NIGMS NIH HHS R01 GM109417
6 · The paper itself

Abstract

Intrinsic motions may allow HIV-1 transactivation response (TAR) RNA to change its conformation to form a functional complex with the Tat protein, which is essential for viral replication. Understanding the dynamic properties of TAR necessitates determining motion on the intermediate nanosecond-to-microsecond time scale. To this end, we performed solid-state deuterium NMR line-shape and T

Indexed as

DeuteriumHIV Long Terminal RepeatMagnetic Resonance SpectroscopyRNA, ViralDeuteriumRNA, Viral

Identifiers

PMID27930881
PMCPMC6785184
OpenAlexW2559976181

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.