ArticleJournal of biomedical optics2016
Penetration depth of photons in biological tissues from hyperspectral imaging in shortwave infrared in transmission and reflection geometries.
Article in Journal of biomedical optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
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Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Medical hyperspectral imaging: an updated review of technology advancements and biomedical applications.Journal of biomedical optics · 2026Pooled it
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- The influence of skin physicochemical properties on electrical sensory sensitivity during transcutaneous electrical nerve stimulation in women.Scientific reports · 2026Article
- Quantitative assessment of rheumatoid arthritis treatment response using short-wave infrared hyperspectral imaging soft abundance scoring.Journal of biomedical optics · 2026Article
- Trinuclear Heptamethine Dyes for Shortwave Infrared In Vivo Imaging.Angewandte Chemie (International ed. in English) · 2026Article
- Dual-Band Infrared PbS Colloidal Quantum Dot Focal Plane Array.Nature communications · 2026Article
- Implanted Miniature Light Devices for Phototherapeutics.Advanced therapeutics · 2026Article
- Versatile and comprehensive hyperspectral imaging tool for molecular neuronavigation: a case study on cerebral gliomas.Journal of biomedical optics · 2025Article
- Wavelet-based compression method for scale-preserving in VNIR and SWIR hyperspectral data.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Optical coherence tomography retinal imaging: narrative review of technological advancements and clinical applications.Annals of translational medicine · 2025Review
- In situ albumin tagging for targeted imaging of endothelial barrier disruption.Science advances · 2025Article
- Photoacoustic imaging of rat kidney tissue oxygenation using second near-infrared wavelengths.Journal of biomedical optics · 2025Article
- Synthesis of Yellow Fluorescence Carbon Dots for the Applications of Vitamin BJournal of fluorescence · 2025Article
- Characterization of Biological Absorption Spectra Spanning the Visible to the Short-Wave Infrared.Journal of visualized experiments : JoVE · 2025Article
- Real-time and non-invasive monitoring of plant signaling by means of optical coherence tomography.Frontiers in plant science · 2025Article
- A Robust NSCLC Biomarker- miR-7-5p: ItsMicroRNA (Shariqah, United Arab Emirates) · 2025Article
- Colour fusion effect on deep learning classification of uveal melanoma.Eye (London, England) · 2024Article
- From bone to nanoparticles: development of a novel generation of bone derived nanoparticles for image guided orthopedic regeneration.Biomaterials science · 2024Article
- Five near-infrared-emissive graphene quantum dots for multiplex bioimaging.2d materials · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Measurement of photon penetration in biological tissues is a central theme in optical imaging. A great number of endogenous tissue factors such as absorption, scattering, and anisotropy affect the path of photons in tissue, making it difficult to predict the penetration depth at different wavelengths. Traditional studies evaluating photon penetration at different wavelengths are focused on tissue spectroscopy that does not take into account the heterogeneity within the sample. This is especially critical in shortwave infrared where the individual vibration-based absorption properties of the tissue molecules are affected by nearby tissue components. We have explored the depth penetration in biological tissues from 900 to 1650 nm using Monte–Carlo simulation and a hyperspectral imaging system with Michelson spatial contrast as a metric of light penetration. Chromatic aberration-free hyperspectral images in transmission and reflection geometries were collected with a spectral resolution of 5.27 nm and a total acquisition time of 3 min. Relatively short recording time minimized artifacts from sample drying. Results from both transmission and reflection geometries consistently revealed that the highest spatial contrast in the wavelength range for deep tissue lies within 1300 to 1375 nm; however, in heavily pigmented tissue such as the liver, the range 1550 to 1600 nm is also prominent.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.