Evidence map›Paper›PMID 27930676›Full record

ArticlePLoS computational biology2016

Stochastic Simulation Service: Bridging the Gap between the Computational Expert and the Biologist.

Brian Drawert, Andreas Hellander, Ben Bales, Debjani Banerjee, Giovanni Bellesia, Bernie J Daigle, Geoffrey Douglas, Mengyuan Gu, Anand Gupta, Stefan Hellander and 7 more

Abstract read
In one paragraph

Article in PLoS computational biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  5. Review
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  11. Programmatic modeling for biological systems.Current opinion in systems biology · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Beyond Deterministic Models in Drug Discovery and Development.Trends in pharmacological sciences · 2020
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Brian DrawertDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.ORCID 0000-0002-0543-8189
Andreas HellanderDepartment of Information Technology, Division of Scientific Computing, Uppsala University, Uppsala, Sweden.
Ben BalesDepartment of Mechanical Engineering, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Debjani BanerjeeDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Giovanni BellesiaDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Bernie J DaigleDepartments of Biological Sciences and Computer Science, The University of Memphis, Memphis, Tennessee, United States of America.
Geoffrey DouglasDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Mengyuan GuDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Anand GuptaDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Stefan HellanderDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Chris HorukDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Dibyendu NathDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Aviral TakkarDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.
Sheng WuDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.ORCID 0000-0002-1626-1729
Per LötstedtDepartment of Information Technology, Division of Scientific Computing, Uppsala University, Uppsala, Sweden.
Chandra KrintzDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.ORCID 0000-0003-4972-0669
Linda R PetzoldDepartment of Computer Science, University of California, Santa Barbara, Santa Barbara, California, United States of America.

Funding

StochSS: A Next-Generation Toolkit for Simulation-Driven Biological DiscoveryR01EB014877 · NIBIB · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI PETZOLD, LINDA R. · 2012 to 2022
$3.9M
Bridging the Gap Between Molecular and Mechanical Control of Cell MorphogenesisR01GM113241 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI CAMPAS, OTGER · 2014 to 2018
$1.7M
NIBIB NIH HHS R01 EB014877NIGMS NIH HHS R01 GM113241
6 · The paper itself

Abstract

We present StochSS: Stochastic Simulation as a Service, an integrated development environment for modeling and simulation of both deterministic and discrete stochastic biochemical systems in up to three dimensions. An easy to use graphical user interface enables researchers to quickly develop and simulate a biological model on a desktop or laptop, which can then be expanded to incorporate increasing levels of complexity. StochSS features state-of-the-art simulation engines. As the demand for computational power increases, StochSS can seamlessly scale computing resources in the cloud. In addition, StochSS can be deployed as a multi-user software environment where collaborators share computational resources and exchange models via a public model repository. We demonstrate the capabilities and ease of use of StochSS with an example of model development and simulation at increasing levels of complexity.

Indexed as

Computer SimulationSoftwareStochastic ProcessesComputational Biology

Identifiers

PMID27930676
PMCPMC5145134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.