ArticleRetinal cases & brief reports
CASE OF METASTATIC UROTHELIAL CARCINOMA OF THE RETINA AND VITREOUS.
Article in Retinal cases & brief reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Insights into Retinal Metastasis from Systemic Carcinoma: A Systematic Review of Clinical and Multimodal Imaging Characteristics.Journal of clinical medicine · 2024Review
- Metastatic tumours to the eye. Review of metastasis to the iris, ciliary body, choroid, retina, optic disc, vitreous, and/or lens capsule.Eye (London, England) · 2023Review
- Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review.Case reports in ophthalmological medicine · 2021Article
- Early penile-only metastasis of urothelial bladder carcinoma.Future science OA · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo report a rare case of vitreo-retinal metastasis from urothelial carcinoma of the bladder.
methodsCase report.
resultsA 55-year-old man with a history of bladder cancer developed atypical vitritis and a white fundus mass. Intravenous fluorescein angiography demonstrated connection between the retinal and tumor vasculature consistent with a retinal malignancy. Cytologic analysis of the vitreous sample revealed large, atypical cells with pleomorphic nuclei, mucin vacuoles, and rare mitotic figures. The cells were immunoreactive for cytokeratin markers AE1/AE3, CK7, and CK20 and the urothelial carcinoma marker GATA3. Review of the patient's initial bladder tumor revealed an anaplastic epithelial neoplasm with dyscohesive cells that appeared histologically identical to those in the vitreous biopsy. Despite external beam radiation therapy, the patient's vision declined and the eye became painful and was ultimately enucleated.
conclusionRetinal metastasis from systemic adenocarcinoma is an extremely rare occurrence with poor prognosis for vision.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.