Evidence map›Paper›PMID 27929803›Full record

ArticlePrion2016

An autopsy-verified case of FTLD-TDP type A with upper motor neuron-predominant motor neuron disease mimicking MM2-thalamic-type sporadic Creutzfeldt-Jakob disease.

Yuichi Hayashi, Yasushi Iwasaki, Akira Takekoshi, Nobuaki Yoshikura, Takahiko Asano, Maya Mimuro, Akio Kimura, Katsuya Satoh, Tetsuyuki Kitamoto, Mari Yoshida and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Prion, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yuichi Hayashia Department of Neurology and Geriatrics , Gifu University Graduate School of Medicine , Gifu , Japan.
Yasushi Iwasakib Department of Neuropathology , Institute for Medical Science of Aging, Aichi Medical University , Nagakute , Japan.
Akira Takekoshia Department of Neurology and Geriatrics , Gifu University Graduate School of Medicine , Gifu , Japan.
Nobuaki Yoshikuraa Department of Neurology and Geriatrics , Gifu University Graduate School of Medicine , Gifu , Japan.
Takahiko Asanoc Department of Radiology , Gifu University Graduate School of Medicine , Gifu , Japan.
Maya Mimurob Department of Neuropathology , Institute for Medical Science of Aging, Aichi Medical University , Nagakute , Japan.
Akio Kimuraa Department of Neurology and Geriatrics , Gifu University Graduate School of Medicine , Gifu , Japan.
Katsuya Satohd Department of Locomotive Rehabilitation Sciences . Nagasaki University Graduate School of Medicine , Nagasaki , Japan.
Tetsuyuki Kitamotoe Division of CJD Science and Technology, Department of Prion Research , Center for Translational and Advanced Animal Research on Human Diseases, Tohoku University School of Medicine , Sendai , Japan.
Mari Yoshidab Department of Neuropathology , Institute for Medical Science of Aging, Aichi Medical University , Nagakute , Japan.
Takashi Inuzukaa Department of Neurology and Geriatrics , Gifu University Graduate School of Medicine , Gifu , Japan.
Gifu University · JPAichi Medical University · JPNagasaki University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we report an autopsy-verified case of frontotemporal lobar degeneration (FTLD)-transactivation responsive region (TAR) DNA binding protein (TDP) type A with upper motor neuron-predominant motor neuron disease mimicking MM2-thalamic-type sporadic Creutzfeldt-Jakob disease (sCJD). A 69-year-old woman presented with an 11-month history of progressive dementia, irritability, insomnia, and gait disturbance without a family history of dementia or prion disease. Neurological examination revealed severe dementia, frontal signs, and exaggerated bilateral tendon reflexes. Periodic sharp-wave complexes were not observed on the electroencephalogram. Brain diffusion MRI did not reveal abnormal changes. An easy Z score (eZIS) analysis for

Indexed as

AgedAutopsyCreutzfeldt-Jakob SyndromeDiagnosis, DifferentialDNA-Binding ProteinsFemaleFrontotemporal Lobar DegenerationHumansMagnetic Resonance ImagingMotor Neuron DiseaseTomography, Emission-Computed, Single-PhotonDNA-Binding Proteinscerebral blood flowfrontotemporal dementiaMM2-thalamic-type sporadic Creutzfeldt-Jakob disease single photon emission computed tomographymotor neuron diseaseTDP43thalamus

Identifiers

PMID27929803
PMCPMC5161298
OpenAlexW2560487929

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.