Evidence map›Paper›PMID 27929530›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2017

Effects of delayed cord clamping on residual placental blood volume, hemoglobin and bilirubin levels in term infants: a randomized controlled trial.

J S Mercer, D A Erickson-Owens, J Collins, M O Barcelos, A B Parker, J F Padbury

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 38 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 5 pooled it
19.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02619006 terminatednot on this map

Effects of Placental Transfusion on Early Brain Development in Infants Born at Term: Follow-Up at 3 & 4 Years of Age

TypeobservationalSponsorUniversity of Rhode IslandRan2015 to 2017Enrolled10ConditionsIron Deficiency, Child DevelopmentArmsDelayed Cord Clamping or Cord Milking
NCT04358822 nacompletednot on this mapstarted 2020, after this paper: background citation

Hemodynamic Effects of Delayed Umbilical Cord Clamping in Full-term Newborns

TypeinterventionalSponsorCairo UniversityRan2020 to 2020Enrolled68ConditionsCardiac Output, High, Cardiac Output, LowArmsDelayed cord clamping
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 5 syntheses or guidelines pooled it, 110 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Umbilical cord milking versus delayed cord clamping in term infants: a systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Pooled it
  4. Guideline
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Article
  17. Review
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

J S MercerCollege of nursing, University of Rhode Island, Kingston, RI, USA.
D A Erickson-OwensCollege of nursing, University of Rhode Island, Kingston, RI, USA.
J CollinsDepartment of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, RI, USA.
M O BarcelosDepartment of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, RI, USA.
A B ParkerDepartment of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, RI, USA.
J F PadburyDepartment of Pediatrics, Alpert School of Medicine, Brown University, Providence, RI, USA.
Brown University · USProvidence College · USWomen & Infants Hospital of Rhode Island · US

Funding

The Developing Brain: Influences and OutcomesUH3OD023313 · OD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI Viren Andrew D'Sa, Daphne Koinis Mitchell · 2018 to 2026
$20.7M
Effects of Placental Transfusion on Early Brain DevelopmentR01HD076589 · NICHD · UNIVERSITY OF RHODE ISLAND · PI DEONI, SEAN CL, ERICKSON-OWENS, DEBRA ANN · 2012 to 2017
$2.3M
NICHD NIH HHS R01 HD076589NIH HHS UH3 OD023313
6 · The paper itself

Abstract

objectiveThe objective of the study was to measure the effects of a 5-min delay (DCC) versus immediate cord clamping (ICC) on residual placental blood volume (RPBV) at birth, and hemoglobin and serum bilirubin at 24 to 48 h of age. STUDY

designIn this prospective randomized controlled trial, 73 women with term (37 to 41 weeks) singleton fetuses were randomized to DCC (⩾5 min; n=37) or ICC (<20 s; n=36).

resultsMaternal and infant demographics were not different between the groups. Mean cord clamping time was 303±121 (DCC) versus 23±59 (ICC) s (P<0.001) with 10 protocol violations. Cord milking was the proxy for DCC (n=11) when the provider could not wait. Infants randomized to DCC compared with ICC had significantly less RPBV (20.0 versus 30.8 ml kg

conclusionTerm infants had early hematological advantage of DCC without increases in hyperbilirubinemia or symptomatic polycythemia.

Indexed as

Placental CirculationAdultBilirubinBlood VolumeConstrictionDelivery, ObstetricFemaleHematocritHemoglobinsHumansInfant, NewbornMalePlacentaPregnancyProspective StudiesRhode IslandBilirubinHemoglobins

Identifiers

PMID27929530
PMCPMC5334141
OpenAlexW2560182427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.