Evidence map›Paper›PMID 27929347›Full record

ArticleExperimental and clinical psychopharmacology2016

Comparing exponential and exponentiated models of drug demand in cocaine users.

Justin C Strickland, Joshua A Lile, Craig R Rush, William W Stoops

Abstract read
In one paragraph

Article in Experimental and clinical psychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  17. (Non-) impact of task experience on behavioral economic decision-making.Experimental and clinical psychopharmacology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Justin C StricklandDepartment of Psychology, University of Kentucky.
Joshua A LileDepartment of Psychology, University of Kentucky.
Craig R RushDepartment of Psychology, University of Kentucky.
William W StoopsDepartment of Psychology, University of Kentucky.

Funding

A Novel Anti Obesity Drug Combination as a Pharmacotherapy for Cocaine DependenceR01DA032254 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2012 to 2015
$1.9M
Medications Development for Cocaine: A Translational Approach in Monkey and HumanR01DA033364 · NIDA · UNIVERSITY OF KENTUCKY · PI LILE, JOSHUA ANTHONY · 2013 to 2016
$1.9M
Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine AbuseR01DA033394 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2013 to 2015
$1.8M
Agonist Replacement Therapy for Methamphetamine Dependence: Human Lab StudiesR01DA025032 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2009 to 2013
$1.8M
Selective Monoamine Release as a Treatment for Cocaine Use DisordersR01DA036553 · NIDA · UNIVERSITY OF KENTUCKY · PI STOOPS, WILLIAM WALTON · 2014 to 2017
$1.6M
Motivation for Cocaine and Non-Drug Reinforcers: Targeting Glutamate HomeostasisR21DA035376 · NIDA · UNIVERSITY OF KENTUCKY · PI STOOPS, WILLIAM WALTON · 2014 to 2015
$376k
Buspirone as a Candidate Medication for Methamphetamine AbuseR21DA035481 · NIDA · UNIVERSITY OF KENTUCKY · PI RUSH, CRAIG R · 2013 to 2014
$374k
A Human Laboratory Study to Investigate Buspirone for Cocaine Use DisordersR21DA034095 · NIDA · UNIVERSITY OF KENTUCKY · PI STOOPS, WILLIAM WALTON · 2012 to 2013
$363k
NIDA NIH HHS R01 DA025032NIDA NIH HHS R01 DA032254NIDA NIH HHS R01 DA033364NIDA NIH HHS R01 DA033394NIDA NIH HHS R01 DA036553NIDA NIH HHS R21 DA034095NIDA NIH HHS R21 DA035376NIDA NIH HHS R21 DA035481
6 · The paper itself

Abstract

Drug purchase tasks provide rapid and efficient measurement of drug demand. Zero values (i.e., prices with zero consumption) present a quantitative challenge when using exponential demand models that exponentiated models may resolve. We aimed to replicate and advance the utility of using an exponentiated model by demonstrating construct validity (i.e., association with real-world drug use) and generalizability across drug commodities. Participants (N = 40 cocaine-using adults) completed Cocaine, Alcohol, and Cigarette Purchase Tasks evaluating hypothetical consumption across changes in price. Exponentiated and exponential models were fit to these data using different treatments of zero consumption values, including retaining zeros or replacing them with 0.1, 0.01, or 0.001. Excellent model fits were observed with the exponentiated model. Means and precision fluctuated with different replacement values when using the exponential model but were consistent for the exponentiated model. The exponentiated model provided the strongest correlation between derived demand intensity (Q0) and self-reported free consumption in all instances (Cocaine r = .88; Alcohol r = .97; Cigarette r = .91). Cocaine demand elasticity was positively correlated with alcohol and cigarette elasticity. Exponentiated parameters were associated with real-world drug use (e.g., weekly cocaine use) whereas these correlations were less consistent for exponential parameters. Our findings show that selection of zero replacement values affects demand parameters and their association with drug-use outcomes when using the exponential model but not the exponentiated model. This work supports the adoption of the exponentiated demand model by replicating improved fit and consistency and demonstrating construct validity and generalizability. (PsycINFO Database Record

Indexed as

Models, EconomicModels, PsychologicalAdultCocaineCocaine-Related DisordersEconomics, BehavioralFemaleHumansMaleMiddle AgedUnited StatesCocaine

Identifiers

PMID27929347
PMCPMC5157700

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.