ArticleNature communications2016
Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 66 citations in OpenAlex.
- Thalamic Activity Regulates Interneuron Density in the Developing Visual Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
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- A Computational Model of the Respiratory CPG for the Artificial Control of Breathing.Bioengineering (Basel, Switzerland) · 2025Article
- Local thalamic interneurons drive spindle termination and enable sleep-dependent learning.bioRxiv : the preprint server for biology · 2025Article
- Development of the early fetal human thalamus: from a protomap to emergent thalamic nuclei.Frontiers in neuroanatomy · 2025Article
- Retinal Input Is Required for the Maintenance of Neuronal Laminae in the Ventrolateral Geniculate Nucleus.eNeuro · 2024Article
- A novel developmental critical period of orexinergic signaling in the primary visual thalamus.iScience · 2024Article
- Review
- The type of inhibition provided by thalamic interneurons alters the input selectivity of thalamocortical neurons.Current research in neurobiology · 2024Article
- Spatiotemporal molecular dynamics of the developing human thalamus.Science (New York, N.Y.) · 2023Article
- Building thalamic neuronal networks during mouse development.Frontiers in neural circuits · 2023Review
- Sonic hedgehog-dependent recruitment of GABAergic interneurons into the developing visual thalamus.eLife · 2022Article
- Visual Deprivation Selectively Reduces Thalamic Reticular Nucleus-Mediated Inhibition of the Auditory Thalamus in Adults.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Development of astrocyte morphology and function in mouse visual thalamus.The Journal of comparative neurology · 2022Article
- Functional Interactions Between the Parafascicular Thalamic Nucleus and Motor Cortex Are Altered in Hemiparkinsonian Rat.Frontiers in aging neuroscience · 2022Article
- Early Development of the GABAergic System and the Associated Risks of Neonatal Anesthesia.International journal of molecular sciences · 2021Review
- Morphology, physiology and synaptic connectivity of local interneurons in the mouse somatosensory thalamus.The Journal of physiology · 2021Article
- Diverse GABAergic neurons organize into subtype-specific sublaminae in the ventral lateral geniculate nucleus.Journal of neurochemistry · 2021Article
- Article
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
The release of GABA from local interneurons in the dorsal lateral geniculate nucleus (dLGN-INs) provides inhibitory control during visual processing within the thalamus. It is commonly assumed that this important class of interneurons originates from within the thalamic complex, but we now show that during early postnatal development Sox14/Otx2-expressing precursor cells migrate from the dorsal midbrain to generate dLGN-INs. The unexpected extra-diencephalic origin of dLGN-INs sets them apart from GABAergic neurons of the reticular thalamic nucleus. Using optogenetics we show that at increased firing rates tectal-derived dLGN-INs generate a powerful form of tonic inhibition that regulates the gain of thalamic relay neurons through recruitment of extrasynaptic high-affinity GABA
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Registered trials
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