ArticleThe British journal of radiology2017
Clinical observation of adverse drug reactions to non-ionic iodinated contrast media in population with underlying diseases and risk factors.
Article in The British journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 68 citations in OpenAlex.
- Iodinated Contrast Media in Oncologic CT: A Narrative Review of Safety, Risk Stratification, and Practical Considerations.Diagnostics (Basel, Switzerland) · 2026Review
- Genetic variations associated with immediate hypersensitivity reactions to iodinated contrast media: A whole exome sequencing study.PloS one · 2026Article
- Risk factor analysis of iodinated contrast medium-related hypersensitivity reactions.Insights into imaging · 2025Review
- Are we systematically overdosing women? Revisiting standardized contrast protocols for thoracoabdominal CT scans.European radiology · 2025Article
- Characterization of Hypersensitivity to Iodinated Contrast Media: Insights from a Six-Year Cohort of 26,465 Procedures.Healthcare (Basel, Switzerland) · 2025Article
- When can coronary computed tomography angiography in patients with calcified plaque be accurate?Frontiers in cardiovascular medicine · 2025Article
- Safety of non-ionic contrast media in CT examinations for out-patients: retrospective multicenter analysis of 473,482 patients.European radiology · 2024Article
- Fasting before contrast-enhanced CT and the incidence of acute adverse reactions: a single-center randomized clinical trial.Insights into imaging · 2024Article
- How to Define and Manage Low-Risk Drug Allergy Labels.The journal of allergy and clinical immunology. In practice · 2024Review
- Organized hematoma of the sphenoid sinus with epistaxis.Radiology case reports · 2024Article
- Association between acute adverse reactions to iodinated contrast media and anxiety in patients undergoing contrast-enhanced CT examination.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Stratified assessment and warning regimen for prevention of acute adverse reactions to iodinated contrast media: results of 150,343 cases in a tertiary hospital.Medical & biological engineering & computing · 2023Article
- Pharmacist-led iodinated contrast media infusion risk assessment service.Frontiers in pharmacology · 2023Article
- Application report of automatic unlocking baseplate in radiotherapy.Journal of applied clinical medical physics · 2022Article
- Hypersensitivity reactions to iodinated radiocontrast media: Cluster analysis reveals distinct clinical phenotypes.The World Allergy Organization journal · 2022Article
- Hypersensitivity Reactions to Iodinated Contrast Media.Biomedicines · 2022Review
- Change the preprocedural fasting policy for contrast-enhanced CT: results of 127,200 cases.Insights into imaging · 2022Article
- Acute Urticaria and Anaphylaxis: Differences and Similarities in Clinical Management.Frontiers in allergy · 2022Review
- Preprocedural fasting for contrast-enhanced CT: when experience meets evidence.Insights into imaging · 2021Review
- Low dose contrast media in step-and-shoot coronary angiography with third-generation dual-source computed tomography: feasibility of using 30 mL of contrast media in patients with body surface area <1.7 mQuantitative imaging in medicine and surgery · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the adverse drug reaction (ADR) profile of non-ionic iodinated contrast media in populations with underlying diseases and risk factors and to provide guidance for more safe and rational use of iodinated contrast media (ICMs) in the clinic.
methodsData from 120,822 cases who underwent enhanced CT examination in our hospital from January 2014 to March 2016 were collected. A standardized case report form was used for data collection and analysis.
resultsThe incidence of ADRs was 0.4% and 0.44% in patients with and without underlying diseases, respectively (p = 0.378). Risk factor analysis revealed that patients with asthma had the highest incidence of ADRs, followed by patients with cardiac insufficiency and patients who were aged had the lowest incidence. There was a low incidence of ADRs in patients under metformin (0.36%) and β-adrenaline receptor antagonist (0.20%) medication. The incidence was the highest in patients with previous ADRs to ICMs (7.17%) and the lowest in those with a history of ICM usage but no previous reactions (0.32%). ADRs were more common in patients at high risk at a higher injection dose (≥100 ml; p < 0.01) and speed (≥5 ml s
conclusionThe incidence of ADRs was extremely low in patients regardless of underlying diseases. Some high-risk factors have certain correlations with the occurrence of ADRs. Particular attention should be given to patients at high risk when performing enhanced CT examination. Advances in knowledge: The correlation between various risk factors and underlying diseases and ADRs was comprehensively analyzed in a large-scale population.
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