Evidence map›Paper›PMID 27928405›Full record

ArticleNeuro-ophthalmology (Aeolus Press)2016

Trauma-Associated Leber Hereditary Optic Neuropathy.

Supanut Apinyawasisuk, Jane W Chan, Anthony C Arnold

Open access · greenAbstract readCase Reports
In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Childhood-Onset Leber Hereditary Optic Neuropathy: Particular Features.International medical case reports journal · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Supanut ApinyawasisukUCLA Department of Ophthalmology, Stein Eye Institute, Los Angeles, California, USA; Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Jane W ChanDepartment of Neurology and Ophthalmology, University of Arizona College of Medicine , Phoenix, Arizona, USA.
Anthony C ArnoldUCLA Department of Ophthalmology , Stein Eye Institute, Los Angeles, California, USA.
King Chulalongkorn Memorial Hospital · THUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 19-year-old man developed visual loss in the left eye 1 day following a martial arts kick to the head. Vision worsened over a week, when visual loss was noted in the right eye without further trauma. The fundus was initially normal, but visual field testing showed temporal depression right eye with diffuse depression left eye, and traumatic chiasmopathy was suspected. Magnetic resonance imaging (MRI) of the brain demonstrated an enlarged chiasm with intrinsic signal abnormality, but no enhancement. Treatment with intravenous corticosteroids and hyperbaric oxygen therapy did not result in visual improvement. Ancillary testing for atypical optic neuritis was negative, but testing for LHON was positive for the 11778 mutation. This case raises the question of trauma as a precipitating factor for LHON and illustrates the rare occurrence of intrinsic signal abnormalities of the chiasm in this disorder.

Indexed as

Chiasmal enlargementLHONMRI abnormalitytrauma

Identifiers

PMID27928405
PMCPMC5123158
OpenAlexW2404710815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.