ArticleNeuro-ophthalmology (Aeolus Press)2016
Syphilitic Optic Neuropathy: Re-emerging Cases Over a 2-Year Period.
Article in Neuro-ophthalmology (Aeolus Press), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic effect of HIV on visual acuity in ocular syphilis: a systematic review.Eye (London, England) · 2023Pooled it
- Clinical outcomes of ocular syphilis within the Great Plains region: potential syndemic impact of methamphetamine use.Eye (London, England) · 2025Observational
- Rapidly Progressive Bilateral Syphilitic Optic Neuritis in an Elderly Patient: A Case Report.Cureus · 2025Article
- Novel and characteristic radiological features of neurosyphilis: a case series.BMC neurology · 2024Article
- Case report: Concurrent MOG antibody-associated disease and latent infections in two patients.Frontiers in immunology · 2024Article
- The case of a 26-year-old male with subacute progressive visual loss.Annals of clinical and translational neurology · 2024Article
- Trends in management of ocular syphilis in tertiary uveitis centre in Prague, Czech Republic.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023Article
- Presentation of Ocular Syphilis with Bilateral Optic Neuropathy.Neuro-ophthalmology (Aeolus Press) · 2023Article
- Ocular syphilis mimicking Vogt-Koyanagi-Harada syndrome: a diagnostic dilemma.Proceedings (Baylor University. Medical Center) · 2023Article
- Diagnosis of Syphilitic Bilateral Papillitis Mimicking Papilloedema.Emerging infectious diseases · 2020Article
- Rapid Administration of High-Dose Intravenous Methylprednisolone Improves Visual Outcomes After Optic Neuritis in Patients With AQP4-IgG-Positive NMOSD.Frontiers in neurology · 2020Article
- Neurosyphilis presenting as visually asymptomatic bilateral optic perineuritis.BMJ case reports · 2019Article
- Optic neuritis caused by the re-emerging great masquerader.BMJ case reports · 2018Article
- Acute Management of Optic Neuritis: An Evolving Paradigm.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2018Review
- Double Morphology: Tertiary Syphilis and Acquired Immunodeficiency Syndrome-A Rare Association.Case reports in dermatological medicine · 2017Article
- Ocular syphilis mimicking Vogt-Koyanagi-Harada disease.Taiwan journal of ophthalmologyArticle
- Nonarteritic Anterior Ischemic Optic Neuropathy and Stroke in Young.Annals of Indian Academy of NeurologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report 7 cases of syphilitic optic neuropathy during a 2-year period. All patients were newly diagnosed with human immunodeficiency virus (HIV) infection. Six cases (86%) initially presented with swollen optic disc either unilaterally or bilaterally. Blind spot enlargement was the most common type of visual field defect. Final visual acuity of at least 20/25 was achieved together with visual field improvement and resolution of swollen optic disc. Optic nerve involvement can be the first manifestation of syphilis and HIV co-infection. Syphilitic optic neuropathy has an excellent prognosis if the disease diagnosed promptly and treated properly.
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