Evidence map›Paper›PMID 27928313›Full record

ArticleNeuro-ophthalmology (Aeolus Press)2014

Adalimumab and Non-Arteritic Anterior Ischaemic Optic Neuropathy: A Case Report.

Krista Kinard, Jessica A Walsh, Gopi K Penmetsa, Judith E A Warner

Open access · greenAbstract readCase Reports
In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Krista KinardDepartment of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah Salt Lake City, Utah USA.
Jessica A WalshDepartment of Internal Medicine (Rheumatology Division), University of Utah Salt Lake City, Utah USA.
Gopi K PenmetsaDepartment of Internal Medicine (Rheumatology Division), University of Utah Salt Lake City, Utah USA.
Judith E A WarnerDepartment of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah Salt Lake City, Utah USA.
University of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sequential anterior ischaemic optic neuropathy was observed in a patient treated with a tumour necrosis factor α (TNF) inhibitor, adalimumab, for ankylosing spondylitis. He developed decreased visual acuity in the right eye after 17 months of treatment. Findings showed right optic disc oedema with haemorrhages and visual field defect. Adalimumab was discontinued and vision stabilised. After restarting adalimumab, he developed optic neuropathy in the left eye. Findings showed optic disc oedema, with haemorrhages and visual field changes in the left eye. Adalimumab may be associated with optic neuropathy; providers prescribing TNF inhibitors should be aware of optic neuropathy as a potential complication.

Indexed as

Adalimumabanterior ischaemic optic neuropathydrugsoptic nervepharmacology

Identifiers

PMID27928313
PMCPMC5122979
OpenAlexW2111203614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.