ArticleJournal of clinical microbiology2017
Validation of Autoclave Protocols for Successful Decontamination of Category A Medical Waste Generated from Care of Patients with Serious Communicable Diseases.
Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- A Day in the Life of a Surgical Instrument: The Cycle of Sterilization.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Review
- Validation of the STERIS Amsco 630LS steam sterilizer autoclave for inactivation of category a medical waste from patients with high-consequence infectious diseases.Infection control and hospital epidemiology · 2024Article
- A narrative review of high-level isolation unit operational and infrastructure features.BMJ global health · 2023Review
- Autoclaving as a Routine Method for the Decontamination of Animal Carcasses in a Biosafety Level 3 Facility.Applied biosafety : journal of the American Biological Safety Association · 2022Article
- Balsam Poplar Buds: Extraction of Potential Phenolic Compounds with Polyethylene Glycol Aqueous Solution, Thermal Sterilization of Extracts and Challenges to Their Application in Topical Ocular Formulations.Antioxidants (Basel, Switzerland) · 2022Article
- The Use of Temperature and Pressure Data Loggers to Validate the Steam Sterilization of Category A Clinical Waste.Applied biosafety : journal of the American Biological Safety Association · 2022Article
- Article
- Investigation of potential safety hazards during medical waste disposal in SARS-CoV-2 testing laboratory.Environmental science and pollution research international · 2021Article
- 2021 American Society for Microbiology Awards Program: Clinical Microbiology Honorees.Journal of clinical microbiology · 2021Article
- Development and Validation of Waste Decontamination Cycle in a Biosafety Level 3 Laboratory.Applied biosafety : journal of the American Biological Safety Association · 2020Article
- Nanopharmaceuticals for Eye Administration: Sterilization, Depyrogenation and Clinical Applications.Biology · 2020Review
- Disposal of the large volume of sputum positive forInfection prevention in practice · 2020Article
- Steam Sterilization of Equine Bone Block: Morphological and Collagen Analysis.BioMed research international · 2018Article
- High-Containment Pathogen Preparation in the Intensive Care Unit.Infectious disease clinics of North America · 2017Review
- Simulation of a Spontaneous Vaginal Delivery and Neonatal Resuscitation in a Biocontainment Unit.Health securityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In response to the Ebola outbreak in 2014, many hospitals designated specific areas to care for patients with Ebola and other highly infectious diseases. The safe handling of category A infectious substances is a unique challenge in this environment. One solution is on-site waste treatment with a steam sterilizer or autoclave. The Johns Hopkins Hospital (JHH) installed two pass-through autoclaves in its biocontainment unit (BCU). The JHH BCU and The Johns Hopkins biosafety level 3 (BSL-3) clinical microbiology laboratory designed and validated waste-handling protocols with simulated patient trash to ensure adequate sterilization. The results of the validation process revealed that autoclave factory default settings are potentially ineffective for certain types of medical waste and highlighted the critical role of waste packaging in successful sterilization. The lessons learned from the JHH validation process can inform the design of waste management protocols to ensure effective treatment of highly infectious medical waste.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.