Evidence map›Paper›PMID 27927805›Full record

ReviewPhysiology (Bethesda, Md.)2017

Transmission of Metabolic Dysfunction Across Generations.

Kathleen Jaeger, Jessica L Saben, Kelle H Moley

Open access · greenAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A Review onGenes · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kathleen JaegerWashington University School of Medicine, St. Louis, Missouri.
Jessica L SabenWashington University School of Medicine, St. Louis, Missouri.
Kelle H MoleyWashington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · US

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2M
MOLECULAR AND METABOLIC ASPECTS OF IMPLANTATIONR01HD065435 · NICHD · WASHINGTON UNIVERSITY · PI KOMMAGANI, RAMAKRISHNA, SANTI, CELIA M · 2010 to 2020
$4.5M
Maternal nutrition and oocyte programmingR01HD083895 · NICHD · WASHINGTON UNIVERSITY · PI ENGLAND, SARAH K. · 2015 to 2019
$2.7M
NICHD NIH HHS R01 HD065435NICHD NIH HHS R01 HD083895NIDDK NIH HHS P30 DK056341
6 · The paper itself

Abstract

Recent human and animal studies investigating the roles of the genome, epigenome, and environmental cues have identified associations between offspring predisposition to life-long obesity/metabolic disease and epigenetic modifications such as DNA methylation. This review explores the mechanisms by which maternal exposures impair the health of not only the next generation but also potentially future generations of offspring.

Indexed as

Epigenesis, GeneticMaternal ExposureMaternal-Fetal ExchangeAnimalsDNA MethylationEndocrine DisruptorsFemaleHistonesHumansMetabolic DiseasesMitochondriaObesityPregnancyEndocrine DisruptorsHistones

Identifiers

PMID27927805
PMCPMC5338595
OpenAlexW2560580902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.