Evidence map›Paper›PMID 27927784›Full record

ArticleJournal of neurophysiology2017

Adenosine-dependent phrenic motor facilitation is inflammation resistant.

Ibis M Agosto-Marlin, Nicole L Nichols, Gordon S Mitchell

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 41 citations in OpenAlex.

  1. Beneficially Stressing the Peripheral Nervous System to Repair.International journal of molecular sciences · 2026
    Review
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  9. Increased spinal adenosine impairs phrenic long-term facilitation in aging rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
    Article
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  20. Spinal AMP kinase activity differentially regulates phrenic motor plasticity.Journal of applied physiology (Bethesda, Md. : 1985) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ibis M Agosto-MarlinDepartment of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin; and.
Nicole L NicholsDepartment of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin; and.
Gordon S MitchellDepartment of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin; and gsmitche@phhp.ufl.edu.
University of Wisconsin–Madison · USUniversity of Florida · US

Funding

Respiratory plasticity and spinal cord InjuryR37HL069064 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MITCHELL, GORDON S. · 2002 to 2011
$4.2M
Intermittent Hypoxia-Induced Inflammation Modulates Respiratory PlasticityR01HL111598 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MITCHELL, GORDON S., WATTERS, JYOTI J · 2012 to 2016
$2.9M
Respiratory Plasticity and Spinal Cord InjuryR01HL069064 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MITCHELL, GORDON S. · 2014 to 2017
$1.5M
Enhanced respiratory plasticity in models of respiratory motor neuron deathR00HL119606 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI NICHOLS, NICOLE L. · 2015 to 2017
$724k
Enhanced respiratory plasticity in models of respiratory motor neuron deathK99HL119606 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI NICHOLS, NICOLE L. · 2014 to 2014
$104k
NHLBI NIH HHS K99 HL119606NHLBI NIH HHS R00 HL119606NHLBI NIH HHS R01 HL069064NHLBI NIH HHS R01 HL111598NHLBI NIH HHS R37 HL069064
6 · The paper itself

Abstract

Phrenic motor facilitation (pMF), a form of respiratory plasticity, can be elicited by acute intermittent hypoxia (i.e., phrenic long-term facilitation, pLTF) or direct application of drugs to the cervical spinal cord. Moderate acute intermittent hypoxia (mAIH; 3 × 5-min episodes of 35-50 mmHg arterial Po

Indexed as

AdenosineAnalysis of VarianceAnimalsBlood GlucoseDisease Models, AnimalDose-Response Relationship, DrugHypoxiaLipopolysaccharidesLong-Term PotentiationMalePhenethylaminesPhrenic NervePurinergic AgentsRatsRats, Sprague-DawleySystemic Inflammatory Response Syndrome2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosineAdenosineBlood Glucoselipid-linked oligosaccharidesLipopolysaccharidesMSX 3 compoundPhenethylaminesPurinergic AgentsXanthinesacute intermittent hypoxiaadenosineinflammationrespiratory plasticityspinal plasticity

Identifiers

PMID27927784
PMCPMC5315699
OpenAlexW2560140827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.