ArticleJournal of the American Society of Nephrology : JASN2017
Genetic Variants Associated with Circulating Parathyroid Hormone.
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Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
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42citing papers in PubMed, 4 pooled it
6.6field-weighted citation impact, top 3% of its field
What it found
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Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Lifestyle factors, serum parameters, metabolic comorbidities, and the risk of kidney stones: a Mendelian randomization study.Frontiers in endocrinology · 2023Pooled it
- Genetic predisposition to increased serum calcium, bone mineral density, and fracture risk in individuals with normal calcium levels: mendelian randomisation study.BMJ (Clinical research ed.) · 2019Pooled it
- Genetic Variants Associated with Circulating Fibroblast Growth Factor 23.Journal of the American Society of Nephrology : JASN · 2018Pooled it
- Genome-wide meta-analysis identifies novel loci associated with parathyroid hormone level.Molecular medicine (Cambridge, Mass.) · 2018Pooled it
- Genetic Variants Associated With the Biochemical Response to Vitamin D3 in the Multi-Ethnic Study of Atherosclerosis.The Journal of clinical endocrinology and metabolism · 2025Trial
- Review
- The Role of Altered Mineral Metabolism in Kidney Stone Disease: Is Vitamin D the Key?American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026Article
- Tubular functional capacity and maladaptive parathyroid hormone response in early-stage chronic kidney disease.Biomolecules & biomedicine · 2025Article
- Diagnosing the silent: the molecular landscape of non-functional parathyroid carcinoma.Virchows Archiv : an international journal of pathology · 2025Review
- Network Interactions of Circulating FGF23, HRG-HMGB1, and Cardiac Disease in CKD.Journal of the American Society of Nephrology : JASN · 2025Article
- Genetic variants predisposing to an increased risk of kidney stone disease.The Journal of clinical investigation · 2025Article
- Pathophysiology of chronic kidney disease-mineral bone disorder (CKD-MBD): from adaptive to maladaptive mineral homeostasis.Clinical kidney journal · 2025Article
- Pathophysiology and therapies of CKD-associated secondary hyperparathyroidism.Clinical kidney journal · 2025Article
- Noncanonical RGS14 structural determinants control hormone-sensitive NPT2A-mediated phosphate transport.The Biochemical journal · 2025Article
- Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.The Journal of clinical endocrinology and metabolism · 2025 · on this mapArticle
- Genetic association of serum calcium, phosphate, vitamin D, parathyroid hormone, and FGF23 with the risk of aortic stenosis.NPJ cardiovascular health · 2024Article
- Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.medRxiv : the preprint server for health sciences · 2024Article
- Epigenetic profiling reveals key genes and cis-regulatory networks specific to human parathyroids.Nature communications · 2024Article
- Serum Calcium, 25-Hydroxyvitamin D, and Parathyroid Hormone Levels in Relation to Aneurysmal Subarachnoid Hemorrhage.Molecular neurobiology · 2023Article
- Association ofGenes · 2023Article
Corrections and comments
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Authors and funding
49 authors at 20 institutions in 9 countries.
Cassianne Robinson-CohenDivision of Nephrology, Department of Medicine, Kidney Research Institute, cassyrc@uw.edu.
Pamela L LutseyDivisions of Epidemiology and Community Health and.
Marcus E KleberVth Department of Medicine, Mannheim Medical Faculty, Heidelberg University, Mannheim, Germany.
Carrie M NielsonDepartment of Public Health and Preventive Medicine, Oregon Health & Science University, Portland, Oregon.
Braxton D MitchellDepartment of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Joshua C BisCardiovascular Health Research Unit, Department of Medicine, and.
Karen M EnyProgram in Genetics & Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada.
Laura PortasInstitute of Population Genetics, National Research Council of Italy, Rome, Italy.
Joel ErikssonDepartment of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, and.
Mattias LorentzonDepartment of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, and.
Daniel L KollerDepartments of Medical and Molecular Genetics and.
Yuri MilaneschiDepartment of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, Vrije Universiteit Medical Center/GGZ inGeest, Amsterdam, The Netherlands.
Alexander TeumerInstitutes for Community Medicine, Department Study of Health in Pomerania - Klinisch-Epidemiologische Forschung (SHIP-KEF), and.
Stefan PilzDepartment of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
Maria NethanderBioinformatics Core Facility, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Elizabeth SelvinDepartment of Epidemiology, Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Weihong TangDivisions of Epidemiology and Community Health and.
Lu-Chen WengDivisions of Epidemiology and Community Health and.
Hoi Suen WongProgram in Genetics & Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada.
Dongbing LaiDepartments of Medical and Molecular Genetics and.
Munro PeacockMedicine, Indiana University, Indianapolis, Indiana.
Anke HannemannClinical Chemistry and Laboratory Medicine, and.
Uwe VölkerDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Georg HomuthDepartment of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
Matthias NaukClinical Chemistry and Laboratory Medicine, and.
Federico MurgiaInstitute of Population Genetics, National Research Council of Italy, Rome, Italy.
Jack W PatteeBiostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota.
Eric OrwollDepartment of Public Health and Preventive Medicine, Oregon Health & Science University, Portland, Oregon.
Joseph M ZmudaDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jose Antonio RianchoDepartment of Medicine, University of Cantabria, and Hospital Universitario Marques de Valdecilla, Insituto de Investigacion Sanitaria, Santander, Spain.
Myles WolfDivision of Nephrology and Hypertension, Department of Medicine and.
Frances WilliamsDepartment of Twin Research and Genetic Epidemiology, Division of Genetics & Molecular Medicine, King's College, London, United Kingdom.
Brenda PenninxDepartment of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, Vrije Universiteit Medical Center/GGZ inGeest, Amsterdam, The Netherlands.
Michael J EconsDepartments of Medical and Molecular Genetics and.
Kathleen A RyanDepartment of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Claes OhlssonDepartment of Internal Medicine and Clinical Nutrition, Centre for Bone and Arthritis Research, and.
Andrew D PatersonProgram in Genetics & Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada.
Bruce M PsatyInstitutes for Community Medicine, Department Study of Health in Pomerania - Klinisch-Epidemiologische Forschung (SHIP-KEF), and.
David S SiscovickDepartment of Epidemiology, University of Washington School of Public Health, Seattle, Washington.
Jerome I RotterDepartment of Pediatrics and Los Angeles Biomedical Research Institute at Harbor-University of California, Los Angeles, Medical Center, Institute for Translational Genomics and Population Sciences, Torrance, California.
Mario PirastuInstitute of Population Genetics, National Research Council of Italy, Rome, Italy.
Elizabeth StreetenDepartment of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Winfried MärzVth Department of Medicine, Mannheim Medical Faculty, Heidelberg University, Mannheim, Germany.
Caroline FoxDepartment of Genetics and Pharmacogenomics, Merck Research, Whitehouse Station, New Jersey.
Josef CoreshDepartment of Epidemiology, Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Henri WallaschofskiClinical Chemistry and Laboratory Medicine, and.
James S PankowDivisions of Epidemiology and Community Health and.
Ian H de BoerDivision of Nephrology, Department of Medicine, Kidney Research Institute.
Bryan KestenbaumDivision of Nephrology, Department of Medicine, Kidney Research Institute.
Oregon Health & Science University · USUniversity of Maryland, Baltimore · USUniversity of Washington · USKidney Research UK · GBHeidelberg University · DEHospital for Sick Children · CAIndiana University – Purdue University Indianapolis · USInstitute for Community Health · USJohns Hopkins University · USUniversity Hospital Heidelberg · DEAmsterdam Neuroscience · NLEMGO Institute for Health and Care Research · NLGGZ inGeest · NLKing's College London · GBMarqués de Valdecilla University Hospital · ESNational Research Council · ITUnited States Department of Veterans Affairs · USUniversitätsmedizin Greifswald · DEUniversity Medical Centre Mannheim · DEUniversity of California, Los Angeles · US
Funding
Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Clinical Research Center (Collaborative U01)U01DK094157 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI Ionut Bebu, Barbara Halina Braffett · 2011 to 2026
$97.6MOregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4MInstitute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8MInstitute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MUCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0MTransgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PETER J TONTONOZ · 2003 to 2026
$40.4MEpidemiology of Diabetes Interventions and Complications Data Coordinating CenterU01DK094176 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI BEBU, IONUT, BRAFFETT, BARBARA HALINA · 2012 to 2022
$30.8MOregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7MClinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MGenome-Wide Association Analysis in Essential Hypertension (FEHGAS study)R01HL086694 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ARAVINDA CHAKRAVARTI · 2007 to 2026
$21.2MResearch BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3MUCLA CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR033176 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2011 to 2011
$15.5MNCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR000128NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR002369NCRR NIH HHS UL1 RR025005NCRR NIH HHS UL1 RR033176NHGRI NIH HHS HHSN268200782096CNHGRI NIH HHS U01 HG004402NHLBI NIH HHS HHSN268200800007CNHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS HHSN268201200036CNHLBI NIH HHS N01 HC055222NHLBI NIH HHS N01 HC085079NHLBI NIH HHS N01 HC085080NHLBI NIH HHS N01 HC085081NHLBI NIH HHS N01 HC085082NHLBI NIH HHS N01 HC085083NHLBI NIH HHS N01 HC085086NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL059367NHLBI NIH HHS R01 HL071051NHLBI NIH HHS R01 HL071205NHLBI NIH HHS R01 HL071250NHLBI NIH HHS R01 HL071251NHLBI NIH HHS R01 HL071258NHLBI NIH HHS R01 HL071259NHLBI NIH HHS R01 HL085251NHLBI NIH HHS R01 HL086694NHLBI NIH HHS R01 HL087641NHLBI NIH HHS R01 HL087652NHLBI NIH HHS R01 HL103612NHLBI NIH HHS R01 HL103706NHLBI NIH HHS R01 HL105756NHLBI NIH HHS R01 HL120393NHLBI NIH HHS U01 HL080295NIAMS NIH HHS K01 AR062655NIAMS NIH HHS R01 AR046838NIAMS NIH HHS U01 AR066160NIA NIH HHS R01 AG023629NIA NIH HHS R01 AG041517NIA NIH HHS U01 AG027810NIA NIH HHS U01 AG042124NIA NIH HHS U01 AG042139NIA NIH HHS U01 AG042140NIA NIH HHS U01 AG042143NIA NIH HHS U01 AG042145NIA NIH HHS U01 AG042168NIDDK NIH HHS K01 DK109019NIDDK NIH HHS K24 DK103986NIDDK NIH HHS K24 DK106414NIDDK NIH HHS P30 DK063491NIDDK NIH HHS P30 DK072488NIDDK NIH HHS U01 DK094157NIDDK NIH HHS U01 DK094176NIGMS NIH HHS T32 GM108557NIMH NIH HHS R01 MH081802NIMH NIH HHS RC2 MH089951NIMH NIH HHS RC2 MH089995Wellcome Trust
Abstract
Parathyroid hormone (PTH) is a primary calcium regulatory hormone. Elevated serum PTH concentrations in primary and secondary hyperparathyroidism have been associated with bone disease, hypertension, and in some studies, cardiovascular mortality. Genetic causes of variation in circulating PTH concentrations are incompletely understood. We performed a genome-wide association study of serum PTH concentrations among 29,155 participants of European ancestry from 13 cohort studies (
Indexed as
Genetic VariationPolymorphism, Single NucleotideAdultAgedEuropeFemaleGenome-Wide Association StudyHumansMaleMiddle AgedParathyroid HormoneParathyroid Hormonegenome-wide association studyhuman geneticsmineral metabolismparathyroid hormone
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