Evidence map›Paper›PMID 27927655›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Role of cannabinoid receptor type 1 in tibial and pudendal neuromodulation of bladder overactivity in cats.

Xuewen Jiang, Michelle Yu, Jamie Uy, Thomas W Fuller, Cameron Jones, Bing Shen, Jicheng Wang, James R Roppolo, William C de Groat, Changfeng Tai

Abstract readComparative Study
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Cats and cannabinoids: past, present and future.Journal of feline medicine and surgery · 2025
    Review
  2. Review
  3. Article
  4. Glutamatergic Mechanisms Involved in Bladder Overactivity and Pudendal Neuromodulation in Cats.The Journal of pharmacology and experimental therapeutics · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Xuewen JiangDepartment of Urology, Qilu Hospital, Shandong University, Jinan, Peoples Republic of China.
Michelle YuDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Jamie UyDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Thomas W FullerDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Cameron JonesDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Bing ShenDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Jicheng WangDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
James R RoppoloDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
William C de GroatDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Changfeng TaiDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; and cftai@pitt.edu.
University of Pittsburgh · USQilu Hospital of Shandong University · CN

Funding

Bladder Nociception: function/central projection of Sympathetic Afferent PathwayR01DK091253 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEGROAT, WILLIAM C · 2011 to 2015
$1.7M
Neurotransmitter Receptors Involved in Neuromodulation of Bladder OveractivityR01DK102427 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAI, CHANGFENG · 2014 to 2017
$924k
Central Sites of Action for Bladder NeuromodulationR01DK094905 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAI, CHANGFENG · 2013 to 2016
$922k
NIDDK NIH HHS R01 DK091253NIDDK NIH HHS R01 DK094905NIDDK NIH HHS R01 DK102427
6 · The paper itself

Abstract

The role of cannabinoid type 1 (CB1) receptors in tibial and pudendal neuromodulation of bladder overactivity induced by intravesical infusion of 0.5% acetic acid (AA) was determined in α-chloralose anesthetized cats. AA irritation significantly (

Indexed as

UrodynamicsAcetic AcidAnimalsBrainCannabinoid Receptor AntagonistsCatsDisease Models, AnimalElectric Stimulation TherapyFemaleMalePudendal NerveReceptor, Cannabinoid, CB1Signal TransductionTibial NerveUrinary BladderUrinary Bladder, OveractiveAcetic AcidCannabinoid Receptor AntagonistsReceptor, Cannabinoid, CB1bladdercannabinoidneuromodulationpudendaltibial

Identifiers

PMID27927655
PMCPMC5374309
OpenAlexW2559827626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.