Evidence map›Paper›PMID 27927632›Full record

Observational studyJournal of the American Heart Association2016

Associations Between Blood Pressure and Outcomes Among Blacks in the Jackson Heart Study.

Tiffany C Randolph, Melissa A Greiner, Chidiebube Egwim, Adrian F Hernandez, Kevin L Thomas, Lesley H Curtis, Paul Muntner, Wei Wang, Robert J Mentz, Emily C O'Brien

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tiffany C RandolphDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC tiffany.randolph@conehealth.com.
Melissa A GreinerDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Chidiebube EgwimDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Adrian F HernandezDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Kevin L ThomasDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Lesley H CurtisDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Paul MuntnerDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, AL.
Wei WangCenter of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS.
Robert J MentzDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Emily C O'BrienDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.

Funding

A Collaboration for Improving Outcomes of African Americans with Heart FailureR01HL117305 · NHLBI · DUKE UNIVERSITY · PI CURTIS, LESLEY H, O'BRIEN, EMILY C · 2013 to 2016
$963k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS R01 HL117305
6 · The paper itself

Abstract

backgroundIn 2014, new hypertension guidelines liberalized blood pressure goals for persons 60 years and older. Little is known about the implications for blacks. METHODS AND

resultsUsing data from 2000 through 2011 for 5280 participants in the Jackson Heart Study, a community-based black cohort in Jackson, Mississippi, we examined whether higher blood pressure was associated with greater risk of mortality and heart failure hospitalization, and whether the risk was the same across age groups. We investigated associations between baseline blood pressure and both mortality and heart failure hospitalization. We also tested for interactions between age and blood pressure in the mortality model. Median systolic and diastolic blood pressures at baseline were 125 mm Hg (25th-75th percentile, 114-137 mm Hg) and 79 mm Hg (72-86 mm Hg), respectively. Median follow-up was 9 years for mortality and 7 years for heart failure hospitalization. After multivariable adjustment, every 10 mm Hg increase in systolic blood pressure was associated with greater risks of mortality (hazard ratio, 1.12; 95% CI, 1.06-1.17) and heart failure hospitalization (1.07; 95% CI, 1.00-1.14). The mortality risk per 10 mm Hg increase in systolic blood pressure was greater in participants younger than 60 years (1.26; 95% CI, 1.13-1.42) than among participants 60 years and older (1.09; 95% CI, 1.03-1.15).

conclusionsAdults in all age groups were at greater risk of mortality as systolic blood pressure increased. In the context of the 2014 hypertension guidelines, these findings should be considered when determining treatment goals in black patients.

Indexed as

AgedBlack or African AmericanBlood PressureFemaleHeart FailureHospitalizationHumansHypertensionMaleMiddle AgedMississippiProspective StudiesRisk FactorsBlacksheart failurehospitalizationhypertensionmortality

Identifiers

PMID27927632
PMCPMC5210402

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.