ArticleEpidemiology and psychiatric sciences2018
The long-term mental health risk associated with non-heterosexual orientation.
Article in Epidemiology and psychiatric sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Mediators of the Disparities in Depression Between Sexual Minority and Heterosexual Individuals: A Systematic Review.Archives of sexual behavior · 2021Pooled it
- Associated factors of depression, anxiety, and suicide behavior among men in Switzerland: findings from the Swiss health survey 2022.Frontiers in psychology · 2026Article
- Association Between Climate Change Awareness and Depression & Anxiety: Findings from a U.S. Sample.International journal of environmental research and public health · 2025Article
- Increased risks for mental disorders among LGB individuals: cross-national evidence from the World Mental Health Surveys.Social psychiatry and psychiatric epidemiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsFindings that describe the mental health risk associated with non-heterosexual orientation in young and middle-aged adults are from cross-sectional designs or fail to discriminate homosexual and bisexual orientations. This study examines the mental health risk of homosexual and bisexual orientation over an 8-year period.
methodsParticipants were from the age-cohort study, the Personality and Total Health Through Life Project, were observed twice every 4 years, and aged 20-24 (n = 2353) and 40-44 (n = 2499) at baseline.
resultsHomosexual orientation was unrelated to long-term depression risk. Risk for anxiety and depression associated with homosexual and bisexual orientations, respectively, were attenuated in fully-adjusted models. Bisexual orientation risk associated with anxiety was partially attenuated in fully-adjusted models.
conclusionsNon-heterosexual orientation was not a major risk factor for long-term mental health outcomes. Instead, those with a non-heterosexual orientation were more likely to experience other mental health risk factors, which explain most of the risk observed amongst those with a non-heterosexual orientation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.