Evidence map›Paper›PMID 27927232›Full record

ArticleJournal of biomedical semantics2016

Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

Masashi Yokochi, Naohiro Kobayashi, Eldon L Ulrich, Akira R Kinjo, Takeshi Iwata, Yannis E Ioannidis, Miron Livny, John L Markley, Haruki Nakamura, Chojiro Kojima and 1 more

Abstract read
In one paragraph

Article in Journal of biomedical semantics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Biological Magnetic Resonance Data Bank.Nucleic acids research · 2023
    Article
  2. Review
  3. Deconstructing the STAR File Format.Balisage series on markup technologies · 2021
    Article
  4. Review
  5. New tools and functions in data-out activities at Protein Data Bank Japan (PDBj).Protein science : a publication of the Protein Society · 2018
    Article
  6. Article
  7. Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive.Methods in molecular biology (Clifton, N.J.) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Masashi YokochiInstitute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Naohiro KobayashiInstitute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Eldon L UlrichDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Akira R KinjoInstitute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Takeshi IwataInstitute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yannis E IoannidisDepartment of Informatics & Telecommunications, University of Athens, Athens, Greece.
Miron LivnyDepartment of Computer Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA.
John L MarkleyDepartment of Biochemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Haruki NakamuraInstitute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Chojiro KojimaInstitute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Toshimichi FujiwaraInstitute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. tfjwr@protein.osaka-u.ac.jp.

Funding

Biological Magnetic Resonance Databank: Metabolomics / Small Molecule ActivitiesP41LM005799 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 1996 to 2013
$12.6M
TR&D 3: TECHNOLOGY DEVELOPMENT FOR NMR STUDIES OF SMALL MOLECULES (METABOLOMICS, NATURAL PRODUCTS, METABOLITE-PROTEIN INTERACTIONS) pp.537-585 P41GM103399 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 2012 to 2019
$9.4M
The BMRB as an evolving resource for biomolecular structure-function researchR01GM109046 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HOCH, JEFFREY C · 2014 to 2022
$6.6M
NIGMS NIH HHS P41 GM103399NIGMS NIH HHS R01 GM109046NLM NIH HHS P41 LM005799
6 · The paper itself

Abstract

backgroundThe nuclear magnetic resonance (NMR) spectroscopic data for biological macromolecules archived at the BioMagResBank (BMRB) provide a rich resource of biophysical information at atomic resolution. The NMR data archived in NMR-STAR ASCII format have been implemented in a relational database. However, it is still fairly difficult for users to retrieve data from the NMR-STAR files or the relational database in association with data from other biological databases.

findingsTo enhance the interoperability of the BMRB database, we present a full conversion of BMRB entries to two standard structured data formats, XML and RDF, as common open representations of the NMR-STAR data. Moreover, a SPARQL endpoint has been deployed. The described case study demonstrates that a simple query of the SPARQL endpoints of the BMRB, UniProt, and Online Mendelian Inheritance in Man (OMIM), can be used in NMR and structure-based analysis of proteins combined with information of single nucleotide polymorphisms (SNPs) and their phenotypes.

conclusionsWe have developed BMRB/XML and BMRB/RDF and demonstrate their use in performing a federated SPARQL query linking the BMRB to other databases through standard semantic web technologies. This will facilitate data exchange across diverse information resources.

Indexed as

Biological OntologiesInternetNuclear Magnetic Resonance, BiomolecularSemanticsDatabases, ProteinProteinsProteinsBMRBDatabaseNMRRDFXML

Identifiers

PMID27927232
PMCPMC5143449

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.