Evidence map›Paper›PMID 27927190›Full record

Observational studyBMC infectious diseases2016

CD4-cell counts and presence of AIDS in HIV-positive patients entering specialized care-a comparison of migrant groups in the German ClinSurv HIV Cohort Study, 1999-2013.

Nadine Zeitlmann, Barbara Gunsenheimer-Bartmeyer, Claudia Santos-Hövener, Christian Kollan, Matthias An der Heiden, ClinSurv Study Group

Open access · goldAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Nadine ZeitlmannPostgraduate Training for Applied Epidemiology (PAE), Robert Koch Institute, Berlin, Germany. ZeitlmannN@rki.de.
Barbara Gunsenheimer-BartmeyerDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Claudia Santos-HövenerDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Christian KollanDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Matthias An der HeidenDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
ClinSurv Study Group
Robert Koch Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough early presentation to HIV-care is essential to ensure timely initiation of antiretroviral therapy, recent studies have shown that especially migrants present to HIV-care at a later stage of HIV-infection. Currently, thirty percent of all newly diagnosed HIV cases in Germany originate from abroad. So far it is unknown, which specific migrant groups in Germany are particularly at risk for late presentation to HIV-care.

methodsWe used data from the Clinical Surveillance of HIV Disease (ClinSurv) cohort, a multi-centre observational cohort (01/01/1999 and 31/07/2013) and included treatment-naïve patients with valid information on country of origin and date of enrolment. Migrants were patients with country of origin outside Germany. We compared time trends for percentage of AIDS (CDC Stage C) and mean CD4-count at enrolment between migrants from Western Europe (WE), Central Europe (CE), Eastern Europe (EE), Sub-Saharan Africa (SSA), South East Asia (SEA) and non-migrants using multivariable regressions. Male non-migrants with mean age of 38-years constituted the reference group.

resultsIn total, 10,211 patients fulfilled the inclusion criteria, of which 2784 were migrants (SSA: 42%, CE: 17%, WE: 11%, EE: 10%, SEA: 9%). The percentage of patients with AIDS at enrolment was higher in SSA (Odds Ratio (OR)

conclusionsSSA and SEA-migrants in Germany present to HIV-care at a later stage of HIV infection than non-migrants. Additionally, previous research found a higher risk for late HIV-testing for migrants. Collecting information about the arrival date of migrants in Germany in the HIV notification system would help to understand to which extent these problems could be tackled in Germany. Moreover, participatory approaches for HIV-testing and care as well as research regarding knowledge, behaviour and attitudes towards these topics for SSA and SEA migrants should be expanded.

Indexed as

CD4 Lymphocyte CountAcquired Immunodeficiency SyndromeAdultAfrica South of the SaharaCohort StudiesEuropeFemaleGermanyHIV InfectionsHumansMaleMiddle AgedTransients and MigrantsAIDSCareCD4GermanyHIVLate presentationMigrantsSouth-East AsiaSub-Saharan Africa

Identifiers

PMID27927190
PMCPMC5142349
OpenAlexW2560506222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.