Evidence map›Paper›PMID 27927074›Full record

ArticlePharmaceutical biology2017

Protective activity of Hertia cheirifolia extracts against DNA damage, lipid peroxidation and protein oxidation.

Seoussen Kada, Hamama Bouriche, Abderrahmane Senator, Ibrahim Demirtaş, Tevfik Özen, Bircan Çeken Toptanci, Göksel Kızıl, Murat Kızıl

Abstract readComparative Study
In one paragraph

Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Flavonoids fromFrontiers in nutrition · 2022
    Article
  3. Hemoglobin Precipitation: An Index ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  4. Article
  5. Variations in the antioxidant and free radical scavenging under induced heavy metal stress expressed as proline content in chickpea.Physiology and molecular biology of plants : an international journal of functional plant biology · 2019
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seoussen Kadaa Laboratory of Applied Biochemistry, Faculty of SNV , University Ferhat Abbas , Sétif , Algeria.
Hamama Bourichea Laboratory of Applied Biochemistry, Faculty of SNV , University Ferhat Abbas , Sétif , Algeria.
Abderrahmane Senatora Laboratory of Applied Biochemistry, Faculty of SNV , University Ferhat Abbas , Sétif , Algeria.
Ibrahim Demirtaşb Department of Chemistry, Faculty of Science , Cankırı Karatekin University , Cankırı , Turkey.
Tevfik Özenc Department of Chemistry, Faculty of Science and Arts , Ondokuz Mayis University , Samsun , Turkey.
Bircan Çeken Toptancid Department of Chemistry, Faculty of Science and Arts , University of Dicle , Diyarbakır , Turkey.
Göksel Kızıld Department of Chemistry, Faculty of Science and Arts , University of Dicle , Diyarbakır , Turkey.
Murat Kızıld Department of Chemistry, Faculty of Science and Arts , University of Dicle , Diyarbakır , Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextHertia cheirifolia L. (Asteraceae), a perennial shrub widely distributed in Northern Africa, is traditionally used to treat inflammatory disorders.

objectiveThe protective effect of methanol (Met E) and aqueous (Aq E) extracts of Hertia cheirifolia against DNA, lipid and protein oxidation was investigated. MATERIALS AND

methodsDifferent concentrations (50-1000 μg/mL) of Hertia cheirifolia aerial part extracts were examined against DNA, lipid and protein oxidation induced by H

resultsBoth extracts were rich in polyphenols, flavonoids and tannins, and were able to scavenge DPPH

conclusionsHertia cheirifolia exhibits potent antioxidant activity and protects biomolecules against oxidative damage; hence, it may serve as potential source of natural antioxidant for pharmaceutical applications and food preservation. This is the first report on the protective activity of this plant against biomolecule oxidation.

Indexed as

AntioxidantsAsteraceaebeta CaroteneBiphenyl CompoundsChloridesDNA DamageDose-Response Relationship, DrugFerric CompoundsIron Chelating AgentsLipid PeroxidationMethanolOxidation-ReductionOxidative StressPhytotherapyPicratesPlant Components, Aerial1,1-diphenyl-2-picrylhydrazylAntioxidantsbeta CaroteneBiphenyl CompoundsChloridesferric chlorideFerric CompoundsIron Chelating AgentsMethanolPicratesPlant ExtractsPolyphenolsSolventsTanninsWaterAntioxidant activitybiomolecule lesionsmedicinal plantoxidative stresspolyphenols

Identifiers

PMID27927074
PMCPMC6130743

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.