Evidence map›Paper›PMID 27926937›Full record

ArticlePLoS neglected tropical diseases2016

Intensive Circulation of Japanese Encephalitis Virus in Peri-urban Sentinel Pigs near Phnom Penh, Cambodia.

Julien Cappelle, Veasna Duong, Long Pring, Lida Kong, Maud Yakovleff, Didot Budi Prasetyo, Borin Peng, Rithy Choeung, Raphaël Duboz, Sivuth Ong and 5 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Julien CappelleCIRAD-ES, UPR AGIRs, Montpellier, France.
Veasna DuongInstitut Pasteur du Cambodge, Virology Unit, Phnom Penh, Cambodia.
Long PringRoyal University of Agriculture, Phnom Penh, Cambodia.
Lida KongRoyal University of Agriculture, Phnom Penh, Cambodia.
Maud YakovleffInstitut Pasteur du Cambodge, Epidemiology and Public Health Unit, Phnom Penh, Cambodia.
Didot Budi PrasetyoUnited States Naval Medical Research Unit 2, Phnom Penh, Cambodia.
Borin PengInstitut Pasteur du Cambodge, Virology Unit, Phnom Penh, Cambodia.
Rithy ChoeungInstitut Pasteur du Cambodge, Virology Unit, Phnom Penh, Cambodia.
Raphaël DubozCIRAD-ES, UPR AGIRs, Montpellier, France.
Sivuth OngInstitut Pasteur du Cambodge, Virology Unit, Phnom Penh, Cambodia.
San SornNational Veterinary Research Institute, Phnom Penh, Cambodia.
Philippe DussartInstitut Pasteur du Cambodge, Virology Unit, Phnom Penh, Cambodia.
Arnaud TarantolaInstitut Pasteur du Cambodge, Epidemiology and Public Health Unit, Phnom Penh, Cambodia.
Philippe BuchyGlaxoSmithKline Vaccines R&D, Singapore, Singapore.
Véronique ChevalierCIRAD-ES, UPR AGIRs, Montpellier, France.
Institut Pasteur du Cambodge · KHRoyal University of Agriculture, Cambodia · KHCambodia-Oxford Medical Research Unit · KHCentre de Coopération Internationale en Recherche Agronomique pour le Développement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the increased use of vaccination in several Asian countries, Japanese Encephalitis (JE) remains the most important cause of viral encephalitis in Asia in humans with an estimated 68,000 cases annually. Considered a rural disease occurring mainly in paddy-field dominated landscapes where pigs are amplifying hosts, JE may nevertheless circulate in a wider range of environment given the diversity of its potential hosts and vectors. The main objective of this study was to assess the intensity of JE transmission to pigs in a peri-urban environment in the outskirt of Phnom Penh, Cambodia. We estimated the force of JE infection in two cohorts of 15 sentinel pigs by fitting a generalised linear model on seroprevalence monitoring data observed during two four-month periods in 2014. Our results provide evidence for intensive circulation of JE virus in a periurban area near Phnom Penh, the capital and most populated city of Cambodia. Understanding JE virus transmission in different environments is important for planning JE virus control in the long term and is also an interesting model to study the complexity of vector-borne diseases. Collecting quantitative data such as the force of infection will help calibrate epidemiological model that can be used to better understand complex vector-borne disease epidemiological cycles.

Indexed as

AnimalsAntibodies, ViralCambodiaCohort StudiesCulexEncephalitis, JapaneseEncephalitis Virus, JapaneseFemaleInsect VectorsSeasonsSeroepidemiologic StudiesSwineSwine DiseasesAntibodies, Viral

Identifiers

PMID27926937
PMCPMC5142769
OpenAlexW2560204505

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.