ArticlePLoS neglected tropical diseases2016
Serological and Virological Evidence of Crimean-Congo Haemorrhagic Fever Virus Circulation in the Human Population of Borno State, Northeastern Nigeria.
Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Crimean-Congo Hemorrhagic Fever Virus in Africa: Epidemiological Trends, Transmission Ecology, Hotspot Heterogeneity, and Preparedness Challenges-A Narrative Review.Tropical medicine and infectious disease · 2026Review
- Bite by bite: Exposing hidden tick-borne disease risks among Nigeria's ruminant livestock workers.One health (Amsterdam, Netherlands) · 2026Article
- Widespread circulation of Crimean-Congo haemorrhagic fever virus in ticks, Corsica (France), 2024.One health (Amsterdam, Netherlands) · 2026Article
- A qualitative risk assessment of Crimean-Congo haemorrhagic fever in Nigeria: implications for One Health response.International health · 2026Article
- Sero-epidemiology of Crimean-Congo haemorrhagic fever in mixed crop-livestock farming households in Burkina Faso: a one health study.PloS one · 2026Article
- Serologic Evidence of Circulation of Six Arboviruses (Dengue Virus, Chikungunya Virus, Zika Virus, Rift Valley Virus, Yellow Fever Virus, Crimean-Congo Hemorrhagic Fever Virus) in Four Regions of Burkina Faso, West Africa.Tropical medicine and infectious disease · 2025Article
- Genetic tracking of Crimean-Congo haemorrhagic orthonairovirus in Hyalomma population infesting cattle in Nigeria.PloS one · 2025Article
- Investigating Crimean-Congo haemorrhagic fever virus seropositivity in camels and human behavioural risks in an abattoir in Nigeria.Epidemiology and infection · 2024Article
- Article
- Tick-Borne Diseases of Humans and Animals in West Africa.Pathogens (Basel, Switzerland) · 2023Review
- Article
- Detection of Crimean-Congo Hemorrhagic Fever Virus Antibodies in Cattle in Plateau State, Nigeria.Viruses · 2022Article
- Seroepidemiology of Crimean-Congo Haemorrhagic Fever among cattle in Cameroon: Implications from a One Health perspective.PLoS neglected tropical diseases · 2022Article
- Crimean-Congo Hemorrhagic Fever Virus in Asia, Africa and Europe.Microorganisms · 2021Review
- Article
- Epidemiology of Crimean-Congo Hemorrhagic Fever (CCHF) in Africa-Underestimated for Decades.The American journal of tropical medicine and hygiene · 2021Review
- Phylogenetic Characterization of Crimean-Congo Hemorrhagic Fever Virus Detected in African Blue Ticks Feeding on Cattle in a Ugandan Abattoir.Microorganisms · 2021Article
- Prevalence of Antibodies to Crimean-Congo Hemorrhagic Fever Virus in Ruminants, Nigeria, 2015.Emerging infectious diseases · 2020Article
- Crimean-Congo Hemorrhagic Fever Virus: Advances in Vaccine Development.BioResearch open access · 2020Review
- Emerging viruses and current strategies for vaccine intervention.Clinical and experimental immunology · 2019Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite several studies on the seroprevalence of antibodies against Crimean-Congo Haemorrhagic Fever virus (CCHFV) from humans and cattle in Nigeria, detailed investigation looking at IgG and IgM have not been reported. Additionally, there have been no confirmed cases of human CCHFV infection reported from Nigeria. PRINCIPAL
findingsSamples from sera (n = 1189) collected from four Local Government Areas in Borno State (Askira/Uba, Damboa, Jere and Maiduguri) were assessed for the presence of IgG and IgM antibodies. The positivity rates for IgG and IgM were 10.6% and 3.5%, respectively. Additionally, sera from undiagnosed febrile patients (n = 380) were assessed by RT-PCR assay for the presence of CCHFV RNA. One positive sample was characterised by further by next generation sequencing (NGS) resulting in complete S, M and L segment sequences.
conclusionsThis article provides evidence for the continued exposure of the human population of Nigeria to CCHFV. The genomic analysis provides the first published evidence of a human case of CCHFV in Nigeria and its phylogenetic context.
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