Evidence map›Paper›PMID 27925867›Full record

ArticleSubstance abuse

Psychosocial stressors and alcohol use, severity, and treatment receipt across human immunodeficiency virus (HIV) status in a nationally representative sample of US residents.

Emily C Williams, Young Sun Joo, Lauren Lipira, Joseph E Glass

Open access · greenAbstract read
In one paragraph

Article in Substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Emily C Williamsa Health Services Research & Development (HSR&D) , Center of Innovation for Veteran-Centered and Value-Driven Care, Veterans Affairs (VA) Puget Sound Health Care System , Seattle , Washington , USA.
Young Sun Jooc Group Health Research Institute , Seattle, Washington , USA.
Lauren Lipirab Department of Health Services , University of Washington , Seattle , Washington , USA.
Joseph E Glassc Group Health Research Institute , Seattle, Washington , USA.
Kaiser Permanente Washington Health Research Institute · USUniversity of Washington · USVA Puget Sound Health Care System · US

Funding

Racial/ethnic Disparities in Alcohol Outcomes and Health ServiceR03AA023639 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI GLASS, JOSEPH EDWIN · 2015 to 2016
$154k
Implementation Research for Evidence-based Care for Alcohol DependenceIK2HX001161 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI WILLIAMS, EMILY CATERINA · 2015 to 2015
–
HSRD VA IK2 HX001161NIAAA NIH HHS R03 AA023639
6 · The paper itself

Abstract

backgroundHuman immunodeficiency virus (HIV) is stigmatized and disproportionately impacts vulnerable populations. Thus, people living with HIV (PLWH) may have greater exposure to psychosocial stressors than those without HIV. Exposure to psychosocial stressors may increase alcohol use and serve as barriers to alcohol treatment receipt. The authors evaluate whether psychosocial stressors and alcohol use, symptom severity, and treatment receipt vary across HIV status in a general population sample of US residents and assess whether psychosocial stressors mediate identified associations.

methodsData from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) were used to assess associations between HIV status and psychosocial stressors (perceived stress, alcohol-related stigma, and perceived discrimination based on race/ethnicity, sexual orientation, or sex) and alcohol-related outcomes (any use, heavy drinking, symptom severity, and treatment receipt). For each outcome, regression models were fit and iteratively adjusted for sociodemographic characteristics and comorbidities. Indirect effects of HIV on alcohol-related outcomes through stressors were estimated to assess mediation when main effects were significant.

resultsAmong 34,653 NESARC Wave 2 respondents, 161 were PLWH. PLWH were more likely than those without HIV to experience discrimination and had higher levels of perceived stress than those without HIV (P values <.05), but the 2 groups did not differ regarding alcohol-related stigma. PLWH were less likely to use alcohol and had similar rates of heavy drinking relative to participants without HIV, but alcohol symptom severity and treatment receipt were greater among PLWH. Perceived stress but not discrimination mediated associations.

conclusionsFindings from this first study of variation in psychosocial stressors and alcohol use, severity, and treatment receipt across HIV status further highlight PLWH as a population that is particularly vulnerable to experiences of psychosocial stress and certain adverse alcohol-related outcomes. Future longitudinal research is needed in a larger sample of PLWH to identify intervention targets.

Indexed as

AdultAgedAlcohol DrinkingAlcohol-Related DisordersCase-Control StudiesComorbidityFemaleHIV InfectionsHumansMaleMiddle AgedPatient Acceptance of Health CareSeverity of Illness IndexStress, PsychologicalUnited StatesYoung AdultAIDSalcoholdiscriminationHIVstigmastress

Identifiers

PMID27925867
PMCPMC5561530
OpenAlexW2560016134

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.