Evidence map›Paper›PMID 27925843›Full record

ArticleHuman vaccines & immunotherapeutics2017

Incidence of herpes zoster and post-herpetic neuralgia in Italy: Results from a 3-years population-based study.

Cristiano Alicino, Cecilia Trucchi, Chiara Paganino, Ilaria Barberis, Sara Boccalini, Domenico Martinelli, Barbara Pellizzari, Angela Bechini, Andrea Orsi, Paolo Bonanni and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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  6. Trends in public interest and vaccination coverage for Herpes Zoster.Public health in practice (Oxford, England) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Cristiano Alicinoa Department of Health Sciences , University of Genoa , Genoa , Italy.
Cecilia Trucchia Department of Health Sciences , University of Genoa , Genoa , Italy.
Chiara Paganinoa Department of Health Sciences , University of Genoa , Genoa , Italy.
Ilaria Barberisa Department of Health Sciences , University of Genoa , Genoa , Italy.
Sara Boccalinib Department of Health Sciences , University of Florence , Florence , Italy.
Domenico Martinellic Department of Medical and Surgical Sciences , University of Foggia , Foggia , Italy.
Barbara Pellizzarid Regional Center for Disease Prevention and Control , Veneto Region , Italy.
Angela Bechinib Department of Health Sciences , University of Florence , Florence , Italy.
Andrea Orsia Department of Health Sciences , University of Genoa , Genoa , Italy.
Paolo Bonannib Department of Health Sciences , University of Florence , Florence , Italy.
Rosa Pratoc Department of Medical and Surgical Sciences , University of Foggia , Foggia , Italy.
Stefania Iannazzoe Ministry of Health , Rome , Italy.
Giancarlo Icardia Department of Health Sciences , University of Genoa , Genoa , Italy.
University of Genoa · ITUniversity of Florence · ITUniversity of Foggia · ITMinistero della Salute · ITRegione del Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes Zoster (HZ) and its main complication, post-herpetic neuralgia (PHN), represent important public health issues because of their relevant burden among older adults. However, data on the epidemiology of HZ and PHN in Italy are very limited. A population-based study was performed by seeking for cases of HZ and PHN, occurred in the period 2013-2015, in the clinical charts of 56 General Practitioners working in 4 Italian Regions (Liguria, Puglia, Toscana and Veneto). The main objective of the study was to estimate the incidence of HZ and the proportion of PHN (at 1 and 3 mo from the onset of HZ; PHN1 and PHN3) among people aged ≥ 50 y. Overall, 598 cases of HZ were identified over 93,146 person-years of observation, thus corresponding to an overall incidence of 6.42 (IC95%: 5.93 - 6.95) HZ cases per 1,000 person-years. The incidence of HZ increased with age and was higher in female than in male. In total, 22.7%, 12.7%, and 2.4% of HZ cases suffered PHN at 1 and 3 mo and 1 y from the onset of acute episode. The proportions of these complications significantly increased with age, with the peak occurring in people aged ≥ 85 y. Four per cent of patients suffered ophthalmic zoster. The study provided an update of the epidemiological burden of HZ and PHN in Italy, confirming the relevant burden of the disease in the elderly population. The study was funded by the Italian Ministry of Health, Center for Disease Prevention and Control (CCM) in 2013.

Indexed as

AgedAged, 80 and overFemaleHerpes ZosterHumansIncidenceItalyMaleMiddle AgedNeuralgia, PostherpeticSex Factorsepidemiologyherpes zosterincidenceItalypost-herpetic neuralgia

Identifiers

PMID27925843
PMCPMC5328218
OpenAlexW2560460586

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.