Evidence map›Paper›PMID 27925656›Full record

ArticleAllergy2017

Mold and dampness exposure and allergic outcomes from birth to adolescence: data from the BAMSE cohort.

J D Thacher, O Gruzieva, G Pershagen, E Melén, J C Lorentzen, I Kull, A Bergström

Open access · hybridAbstract read
In one paragraph

Article in Allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Childhood asthma and mould in homes-A meta-analysis.Wiener klinische Wochenschrift · 2025
    Pooled it
  2. Article
  3. Review
  4. The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases.World journal of otorhinolaryngology - head and neck surgery · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Development of the Respiratory System During Adolescence.Advances in experimental medicine and biology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Indoor Environmental Exposures and Their Relationship to Allergic Diseases.The journal of allergy and clinical immunology. In practice · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Early-life residential exposure to moisture damage is associated with persistent wheezing in a Finnish birth cohort.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

J D ThacherInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
O GruzievaInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
G PershagenInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
E MelénInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
J C LorentzenCentre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.
I KullInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
A BergströmInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Karolinska Institutet · SEStockholm County Council · SESachs' Children and Youth Hospital · SEStockholm South General Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExposure to moldy or damp indoor environments is associated with allergic disease in young children, but it is unclear whether the effects persist to adolescence. Our objective was to assess whether exposure to mold or dampness during infancy increases the risk of asthma, rhinitis, or IgE sensitization in children followed from birth to 16 years of age.

methodsWe collected questionnaire derived reports of mold or dampness indicators and allergic outcomes from 3798 children in a Swedish birth cohort (BAMSE). Sensitization was assessed from blood samples in 3293 children. Longitudinal associations between prevalent asthma, rhinitis, and IgE sensitization and mold or dampness indicators were assessed using generalized estimating equations.

resultsExposure to any mold or dampness indicator was associated with asthma up to 16 years of age (OR 1.31; 95% CI 1.08-1.59), while exposure to mold odor (OR 1.29; 95% CI 1.03-1.62) and visible mold (OR 1.28; 95% CI 1.04-1.58) were associated with rhinitis. Increased risks were observed for nonallergic asthma (OR 1.80; 95% CI 1.27-2.55) and rhinitis (OR 1.41; 95% CI 1.03-1.93). No association was observed between mold or dampness indicators and IgE sensitization. Exposure to any mold or dampness indicator was associated with persistent asthma (OR 1.73; 95% CI 1.20-2.50), but not with early-transient or late-onset asthma.

conclusionExposure to mold or dampness during infancy increased the risk of asthma and rhinitis up to 16 years of age, particularly for nonallergic disease. Early exposure to mold or dampness appeared particularly associated with persistent asthma through adolescence.

Indexed as

AdolescentAir Pollution, IndoorAsthmaChildChild, PreschoolFungiHumansHumidityHypersensitivityInfantInfant, NewbornLongitudinal StudiesMaleRhinitisRisk FactorsSurveys and QuestionnairesasthmaIgE sensitizationindoor environmentrhinitis

Identifiers

PMID27925656
PMCPMC5434946
OpenAlexW2560116215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.