ArticleScientific reports2016
Gsy, a novel glucansucrase from Leuconostoc mesenteroides, mediates the formation of cell aggregates in response to oxidative stress.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Oxidative stress tolerance and antioxidant capacity of lactic acid bacteria as probiotic: a systematic review.Gut microbes · 2020Pooled it
- Cold induced expression of a novel levansucrase gene sacB1 enhances exopolysaccharide production and stress resilience in Leuconostoc mesenteroides.Scientific reports · 2025Article
- Phenotypic variation in growth and biofilm formation ofFrontiers in microbiology · 2025Article
- Applications of Proteomics in Probiotics Having Anticancer and Chemopreventive Properties.Advances in experimental medicine and biology · 2024Article
- Glycosyltransferases Expression Changes inFoods (Basel, Switzerland) · 2023Article
- Imaging Flow Cytometry Demonstrates Physiological and Morphological Diversity within Treated Probiotic Bacteria Groups.International journal of molecular sciences · 2023Article
- Current Trends in the Production of Probiotic Formulations.Foods (Basel, Switzerland) · 2022Review
- Response of Controlled Cell Load Biofilms to Cold Atmospheric Plasma Jet: Evidence of Extracellular Matrix Contribution.Life (Basel, Switzerland) · 2021Article
- Exploring Antibiotic Resistance Diversity inMicroorganisms · 2021Article
- Gut Microbiota: Critical Controller and Intervention Target in Brain Aging and Cognitive Impairment.Frontiers in aging neuroscience · 2021Review
- Petunidin-Based Anthocyanin Relieves Oxygen Stress inFrontiers in microbiology · 2020Article
- Different Modes of Regulation of the Expression of Dextransucrase inFrontiers in microbiology · 2019Article
- High Levels of COApplied and environmental microbiology · 2019Article
- Molecular and Functional Study of a Branching Sucrase-Like Glucansucrase Reveals an Evolutionary Intermediate between Two Subfamilies of the GH70 Enzymes.Applied and environmental microbiology · 2018Article
- Extrusion of Dissolved Oxygen by Exopolysaccharide FromFrontiers in microbiology · 2018Article
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leuconostoc mesenteroides is a member of lactic acid bacteria (LAB) with wide applications in the food and medical industries. Species in the genus Leuconostoc are catalase-negative and generally regarded as facultative anaerobic or aerotolerant organisms. Despite their extensive use in industry, certain issues concerning the aerobic life of L. mesenteroides, e.g., the mechanism involved in the tolerance to oxygen, remain to be addressed. In this manuscript, a survival strategy employed by L. mesenteroides BD3749 in response to oxidative stress was elucidated. BD3749 cells cultivated in medium with sucrose available synthesized large amounts of exopolysaccharides, mostly consisting of insoluble EPS. When BD3749 cells were challenged with oxidative stress, the amount of insoluble EPS was greatly enhanced. The synthesized EPSs reduced the accumulation of reactive oxygen species (ROS) in bacterial cells and improved their survival during chronic oxidative stress. Another study showed that Gsy, a novel glucansucrase in the GH70 family that is induced by sucrose and up-regulated following exposure to oxygen, was responsible for the synthesis of insoluble EPS. Gsy was subsequently demonstrated to play pivotal roles in the formation of aggregates to alleviate the detrimental effects on BD3749 cells exerted by oxygen.
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