SynthesisScientific reports2016
Prognostic implications of aspiration pneumonia in patients with community acquired pneumonia: A systematic review with meta-analysis.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03693027 (Evaluation of a Daily Oral Care Lozenge on Oral Health and Quality of Life in Older Adults), which is not on this map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of a Daily Oral Care Lozenge on Oral Health and Quality of Life in Older Adults
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Pathogenic mechanisms and resistance profiles of microbial pulmonary infections in lung cancer: a systematic review.BMC infectious diseases · 2025Pooled it
- Factors driving outcome variability in aspiration and community-acquired pneumonia: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Characteristics of aspiration pneumonia patients in acute care hospitals: A multicenter, retrospective survey in Northern Japan.PloS one · 2021Trial
- When a Lung Collapses: A Case of Polymicrobial Empyema Presenting as Massive Hydropneumothorax.Cureus · 2026Article
- Aspiration pneumonia in the world's most aged society: age-stratified ICU management and outcomes from a nationwide Japanese registry.Journal of intensive care · 2026Article
- Association of eosinophil levels with 30-day overall mortality in hospitalized patients with aspiration pneumonia.Scientific reports · 2026Article
- Implementing standardized, evidence-based nursing management to prevent aspiration risk in hospitalized older adults.BMC nursing · 2026Article
- Hidden Undernourishment: Sex and Disease Factors Associated with the Underrating of Swallowing Function.Dysphagia · 2026Article
- Facility-Level Factors Associated With Aspiration Pneumonia in Japanese Geriatric Health Service Settings: A Nationwide Cross-Sectional Study.Geriatrics & gerontology international · 2026Observational
- Article
- Quantifying clinical indicators for identifying and prognosticating aspiration pneumonia in Chinese geriatric patients: a retrospective cohort study integrating multivariable regression and interpretable machine learning.Frontiers in medicine · 2026Article
- Post-Stroke Aspiration Pneumonia in Riyadh, Saudi Arabia: A Retrospective Cohort Study.Vascular health and risk management · 2026Article
- A prognostic model for early risk stratification in adult community-acquired suspected CNS infections: multicenter development and external validation.BMC infectious diseases · 2025Article
- Article
- Management of the Diagnosis and Treatment of Pneumonia in an Aging Society.Internal medicine (Tokyo, Japan) · 2025Review
- Coagulation and inflammatory markers independently predict in-hospital mortality in aspiration pneumonia patients undergoing bronchoalveolar lavage.American journal of translational research · 2025Article
- Antibiotics versus Non-Antibiotic in the treatment of Aspiration Pneumonia: analysis of the MIMIC-IV database.BMC pulmonary medicine · 2024Article
- Computed tomography findings of 50 patients diagnosed with aspiration pneumonia: A case series.Journal of general and family medicine · 2024Article
- Article
- Incidence and characteristics of aspiration pneumonia in the Nagasaki Prefecture from 2005 to 2019.BMC pulmonary medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 8 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspiration pneumonia is thought to be associated with a poor outcome in patients with community acquired pneumonia (CAP). However, there has been no systematic review regarding the impact of aspiration pneumonia on the outcomes in patients with CAP. This review was conducted using the MOOSE guidelines: Patients: patients defined CAP. EXPOSURE: aspiration pneumonia defined as pneumonia in patients who have aspiration risk. Comparison: confirmed pneumonia in patients who were not considered to be at high risk for oral aspiration. OUTCOMES: mortality, hospital readmission or recurrent pneumonia. Three investigators independently identified published cohort studies from PubMed, CENTRAL database, and EMBASE. Nineteen studies were included for this systematic review. Aspiration pneumonia increased in-hospital mortality (relative risk, 3.62; 95% CI, 2.65-4.96; P < 0.001, seven studies) and 30-day mortality (3.57; 2.18-5.86; P < 0.001, five studies). In contrast, aspiration pneumonia was associated with decreased ICU mortality (relative risk, 0.40; 95% CI, 0.26-0.60; P < 0.00001, four studies). Although there are insufficient data to perform a meta-analysis on long-term mortality, recurrent pneumonia, and hospital readmission, the few reported studies suggest that aspiration pneumonia is also associated with these poor outcomes. In conclusion, aspiration pneumonia was associated with both higher in-hospital and 30-day mortality in patients with CAP outside ICU settings.
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