Evidence map›Paper›PMID 27924681›Full record

ArticleHuman vaccines & immunotherapeutics2017

Factors associated with 30-day mortality in elderly inpatients with community acquired pneumonia during 2 influenza seasons.

Núria Torner, Conchita Izquierdo, Núria Soldevila, Diana Toledo, Judith Chamorro, Elena Espejo, Amelia Fernández-Sierra, Angela Domínguez, Project PI12/02079 Working Group

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Human vaccines & immunotherapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. [Statement of the Austrian Society of Pneumology (ASP)].Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift · 2020
    Review
  10. Article
  11. Procare : das forbildungsmagazin fur pflegeberufe · 2020
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Núria Tornera CIBER Epidemiology and Public Health (CIBERESP), Carlos III Health Institute , Madrid , Spain.
Conchita Izquierdoc Public Health Agency of Catalonia. Generalitat of Catalonia , Barcelona , Spain.
Núria Soldevilaa CIBER Epidemiology and Public Health (CIBERESP), Carlos III Health Institute , Madrid , Spain.
Diana Toledoa CIBER Epidemiology and Public Health (CIBERESP), Carlos III Health Institute , Madrid , Spain.
Judith Chamorrod Preventive Medicine Service, Complejo Hospitalario de Navarra , Pamplona , Spain.
Elena Espejoe Health Consortium of Terrassa , Terrassa , Spain.
Amelia Fernández-Sierraf Preventive Medicine and Public Health. Complejo Hospitalario Universitario , Granada , Spain.
Angela Domíngueza CIBER Epidemiology and Public Health (CIBERESP), Carlos III Health Institute , Madrid , Spain.
Project PI12/02079 Working Group
Instituto de Salud Carlos III · ESCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESComplejo Hospitalario de Navarra · ESComplejo Hospitalario Universitario de Granada · ESGovernment of Catalonia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Community-acquired pneumonia (CAP) refers to pneumonia unrelated to hospitals or extended-care facilities. The aim of this study was to determine factors associated with 30-day mortality in patients with CAP aged ≥ 65 y admitted to 20 hospitals in 7 Spanish regions during the 2013-14 and 2014-15 influenza seasons. Logistic regression was used to identify factors associated with 30-day mortality. The adjusted model included variables selected by backward elimination with a cut off of < 0.02. A total of 1928 CAP cases were recorded; 60.7% were male, 46.67% were aged 75-84 years, and 30-day mortality was 7.6% (n = 146). Pneumococcal vaccination had a significant protective effect (OR 0.68, 95% CI, 0.48-0.96; p = 0.03) and influenza vaccination in any 3 preceding seasons slight protective effect against CAP (OR 0.72, 95% CI, 0.51-1.02;p = 0.06). Factors significantly associated with 30-day mortality were having a degree of dependence (aOR 3.67, 95% CI, 2.34-5.75; p < 0,001); age ≥ 85 y (OR 3.01, 95% CI, 1.71-5.30; p < 0.001), liver impairment (aOR 2.41, 95% CI, 1.10-5.31; p = 0.03); solid organ neoplasm (aOR 2.24, 95% CI, 1.46-3.45; p < 0.001), impaired cognitive function (aOR 1.93, 95% CI, 1.22-3.05; p = 0.005), and ICU admittance (aOR2.56, 95% CI, 1.27-5.16; p = 0.009); length of stay (aOR 1.56, 95% CI, 1.02 - 2.40; p = 0.04) and cardio-respiratory resuscitation (aOR 7.75, 95% CI, 1.20 - 49.98; p = 0.03). No association was observed for other comorbidities such as chronic pulmonary obstructive disease (COPD) or heart conditions in the adjusted model. Offering both pneumococcal and influenza vaccination to the elderly may improve 30-day mortality in patients with CAP.

Indexed as

AgedAged, 80 and overCase-Control StudiesCommunity-Acquired InfectionsFemaleHospitalizationHumansMalePneumoniaSpainSurvival Analysisagingcommunity acquired pneumoniaelderlymortality

Identifiers

PMID27924681
PMCPMC5328220
OpenAlexW2560571674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.