ArticleCerebellum (London, England)2017
Progression of Gait Ataxia in Patients with Degenerative Cerebellar Disorders: a 4-Year Follow-Up Study.
Article in Cerebellum (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Indexes for motor performance assessment in job integration/reintegration of people with neuromuscular disorders: A systematic review.Frontiers in neurology · 2022Pooled it
- Case Report: A 1-year progression of mediolateral gait instability during tandem walking in FXTAS.Frontiers in sports and active living · 2025Article
- Clinic vs. daily life gait characteristics in patients with spinocerebellar ataxia.Frontiers in digital health · 2025Article
- Mixed Reality-Based Smart Occupational Therapy Personalized Protocol for Cerebellar Ataxic Patients.Brain sciences · 2024Article
- Local Dynamic Stability of Trunk During Gait is Responsive to Rehabilitation in Subjects with Primary Degenerative Cerebellar Ataxia.Cerebellum (London, England) · 2024Article
- Quantitative Gait and Balance Outcomes for Ataxia Trials: Consensus Recommendations by the Ataxia Global Initiative Working Group on Digital-Motor Biomarkers.Cerebellum (London, England) · 2024Review
- Optimizing Rare Disease Gait Classification through Data Balancing and Generative AI: Insights from Hereditary Cerebellar Ataxia.Sensors (Basel, Switzerland) · 2024Article
- Editorial: Job integration/reintegration of people with neuromuscular disorders in the epoch of "industry 4.0".Frontiers in neurology · 2024Article
- Quantitative Characterization of Gait Patterns in Individuals with Spinocerebellar Ataxia 38.Bioengineering (Basel, Switzerland) · 2023Article
- Consensus Paper: Ataxic Gait.Cerebellum (London, England) · 2023Article
- A Proof of Concept Combined Using Mixed Reality for Personalized Neurorehabilitation of Cerebellar Ataxic Patients.Sensors (Basel, Switzerland) · 2023Article
- Neurophysiology of cerebellar ataxias and gait disorders.Clinical neurophysiology practice · 2023Review
- Quasi-passive lower limbs exosuit: an in-depth assessment of fatigue, kinematic and muscular patterns while comparing assistive strategies on an expert subject's gait analysis.Frontiers in neurorobotics · 2023Article
- A BCI System Based on Motor Imagery for Assisting People with Motor Deficiencies in the Limbs.Brain sciences · 2020Article
- Exploring Risk of Falls and Dynamic Unbalance in Cerebellar Ataxia by Inertial Sensor Assessment.Sensors (Basel, Switzerland) · 2019Article
- The Working Life of People with Degenerative Cerebellar Ataxia.Cerebellum (London, England) · 2019Observational
- Consensus Paper: Neurophysiological Assessments of Ataxias in Daily Practice.Cerebellum (London, England) · 2018Review
- Effect of Restraining the Base of Support on the Other Biomechanical Features in Patients with Cerebellar Ataxia.Cerebellum (London, England) · 2018Article
- Partial Body Weight-Supported Treadmill Training in Spinocerebellar Ataxia.Rehabilitation research and practice · 2018Article
- Commentary on the Paper "Progression of Gait Ataxia in Patients with Degenerative Cerebellar Disorders: a 4-Year Follow-Up Study".Cerebellum (London, England) · 2017Article
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, the progression of gait impairment in a group of patients with primary degenerative cerebellar ataxias was observed over a period of 4 years. A total of 30 patients underwent an initial gait analysis study, and thereafter only 12 were evaluated because they completed the 2- and 4-year follow-up evaluations. Time-distance parameters, trunk and joint range of motion (RoM), and variability parameters (e.g., coefficients of variation) were measured at the baseline and at each follow-up evaluation. The scale for the assessment and rating of ataxia (SARA) was used to evaluate disease severity. We found a significant increase in the SARA score at both the 2- and 4-year follow-up evaluations. Almost all the gait variables changed significantly only at the 4-year follow-up. Particularly, we found a significant decrease in the step length and in the hip, knee, and ankle joint RoM values and noted a significant increase in the trunk rotation RoM and stride-to-stride and step length variability. Furthermore, a significant difference in ankle joint RoM was found between spinocerebellar ataxia and sporadic adult-onset ataxia patients, with the value being lower in the former group of patients. Our findings suggest that patients with degenerative cerebellar ataxias exhibit gait decline after 4 years from the baseline. Moreover, patients try to maintain an effective gait by adopting different compensatory mechanisms during the course of the disease in spite of disease progression.
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