ArticleScience signaling2016
Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.
Abstract read
In one paragraph
Article in Science signaling, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers.
0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed
17.4field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
141 citing papers in PubMed, 221 citations in OpenAlex.
- Functions of exosome-derived noncoding RNA-encoded polypeptides/proteins in human diseases.Genes & diseases · 2027Review
- A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Sarcolipin is a Conformation-Dependent Regulator of the Sarcoplasmic Reticulum Calcium Pump SERCA.The Journal of membrane biology · 2026Article
- The identity crisis of cryptic lncRNAs: when non-coding RNAs translate into small peptides.The EMBO journal · 2026Review
- Ribo-ITP enables identification of translons from limited input samples.Nature communications · 2026Article
- Neprilysin mediated cleavage of phospholamban dysregulates SERCA in heart failure.bioRxiv : the preprint server for biology · 2026Article
- Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction, and vascular disease.Cardiovascular research · 2026Article
- A microprotein encoded by FERMT3 modulates endothelial cell protein catabolism and induces cell cycle arrest and senescence.Cell communication and signaling : CCS · 2026Article
- PIGBOS-CLCC1 interaction shapes cellular calcium dynamics and energy metabolism.Cell communication and signaling : CCS · 2026Article
- No Time to Fold: Intrinsically Disordered Microproteins in Action.Biochemistry · 2026Review
- The Landscape of SERCA2 in Cardiovascular Diseases: Expression Regulation, Therapeutic Applications, and Emerging Roles.Biomolecules · 2026Review
- Microprotein, macro-effect: DWORF as a therapeutic strategy in heart failure.Frontiers in cell and developmental biology · 2026Review
- The SERCA-PLN-DWORF axis in cardiometabolic disease: mechanisms and therapeutic perspectives.Cardiovascular diabetology · 2025Review
- Microproteins in Metabolic Biology: Emerging Functions and Potential Roles as Nutrient-Linked Biomarkers.International journal of molecular sciences · 2025Review
- The 'non-conventional' peptidome: A new layer in plant regulatory mechanisms.Plant communications · 2025Review
- Micropeptides in the oncological dark matter: decoding their roles in tumor progression and therapy resistance.Journal of translational medicine · 2025Review
- Glucose tasting depletes intracellular calcium stores and impairs macrophage functionality.iScience · 2025Article
- Allosteric Modulation of SERCA Pumps in Health and Disease: Structural Dynamics, Posttranslational Modifications, and Therapeutic Potential.Journal of molecular biology · 2025Review
- Impacts of systemic milieu on cerebrovascular and brain aging: insights from heterochronic parabiosis, blood exchange, and plasma transfer experiments.GeroScience · 2025Review
- Functional analysis and transcriptional profiling of non-coding RNAs in yeast.The Biochemical journal · 2025Review
81 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Douglas M AndersonDepartment of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. eric.olson@utsouthwestern.edu doug_anderson@urmc.rochester.edu.
Catherine A MakarewichDepartment of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Kelly M AndersonDepartment of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
John M SheltonDepartment of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Svetlana BezprozvannayaDepartment of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Rhonda Bassel-DubyDepartment of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Eric N OlsonDepartment of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. eric.olson@utsouthwestern.edu doug_anderson@urmc.rochester.edu.
The University of Texas Southwestern Medical Center · US
Funding
Microenvironmental control of progenitors in organ dysfunction and repairU01HL100401 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N, SCHNEIDER, JAY W · 2009 to 2015
$8.3MTraining CoreU54HD087351 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N · 2015 to 2019
$7.8MHeart Repair through Reprogramming of Cardiac Cell FateR01HL077439 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N · 2004 to 2015
$6.2MDeciphering the role of a novel micropeptide in cardiac function and dysfunctionR01HL130253 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI BASSEL-DUBY, RHONDA, OLSON, ERIC N · 2016 to 2023
$4.4MMetabolic Control by Myogenic MicroRNAs, Mediator and MyokinesR01DK099653 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI BASSEL-DUBY, RHONDA, OLSON, ERIC N · 2013 to 2016
$1.9MMolecular Dissection of Myoblast Fusion In Muscle Development and RegenerationR01AR067294 · NIAMS · UT SOUTHWESTERN MEDICAL CENTER · PI BASSEL-DUBY, RHONDA, OLSON, ERIC N · 2015 to 2019
$1.8MElucidation of the Role of a Novel Cardiac Micropeptide in the Control of Heart Function and DysfunctionF32HL129674 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI MAKAREWICH, CATHERINE A · 2015 to 2018
$124kNHLBI NIH HHS F32 HL129674NHLBI NIH HHS R01 HL077439NHLBI NIH HHS R01 HL130253NHLBI NIH HHS U01 HL100401NIAMS NIH HHS R01 AR067294NICHD NIH HHS U54 HD087351NIDDK NIH HHS R01 DK099653
Abstract
Micropeptides function as master regulators of calcium-dependent signaling in muscle. Sarco/endoplasmic reticulum Ca
Indexed as
AnimalsCalcium-Binding ProteinsCalcium SignalingChlorocebus aethiopsCOS CellsMaleMiceMuscle ProteinsPeptidesPhospholambanProteolipidsSarcoplasmic Reticulum Calcium-Transporting ATPasesCalcium-Binding ProteinsMuscle Proteinsmyoregulin, mousePeptidesPhospholambanProteolipidssarcolipinSarcoplasmic Reticulum Calcium-Transporting ATPases
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.