Evidence map›Paper›PMID 27923797›Full record

ArticleCirculation. Cardiovascular imaging2016

Is Myocardial Fibrosis a New Frontier for Discovery in Cardiotoxicity Related to the Administration of Anthracyclines?

Giselle C Meléndez, W Gregory Hundley

Abstract readEditorialComment
In one paragraph

Article in Circulation. Cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Cardiac fibrosis in oncologic therapies.Current opinion in physiology · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Cardiac fibroblast activation detected by Ga-68 FAPI PET imaging as a potential novel biomarker of cardiac injury/remodeling.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Giselle C MeléndezFrom the Department of Internal Medicine, Section on Cardiovascular Medicine (G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), and Department of Radiological Sciences (W.G.H.), Wake Forest Health Sciences, Winston-Salem, NC.
W Gregory HundleyFrom the Department of Internal Medicine, Section on Cardiovascular Medicine (G.C.M., W.G.H.), Department of Pathology, Section on Comparative Medicine (G.C.M.), and Department of Radiological Sciences (W.G.H.), Wake Forest Health Sciences, Winston-Salem, NC. ghundley@wakehealth.edu.

Funding

Preventing Anthracycline Cardiovascular Toxicity with StatinsR01HL118740 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2013 to 2018
$4.2M
Understanding and Predicting Fatigue, CV Decline & Events After Breast CA TreatmentR01CA199167 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2015 to 2022
$3.2M
Early Imaging Detection of CV Injury after CancerR01CA167821 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY, JOLLY, MARIE-PIERRE · 2012 to 2016
$2.5M
NCI NIH HHS R01 CA167821NCI NIH HHS R01 CA199167NHLBI NIH HHS R01 HL118740
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnthracyclinesCardiotoxicityAntibiotics, AntineoplasticAntineoplastic AgentsCardiomyopathiesHumansNeoplasmsAnthracyclinesAntibiotics, AntineoplasticAntineoplastic AgentsanthracyclinescardiotoxicityEditorialsfibrosisheartleft ventricular dysfunction

Identifiers

PMID27923797
PMCPMC7869867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.