ArticleNeural development2016
Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brain.
Article in Neural development, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Interpretable and scalable spatial gene set activity analysis with GESSO uncovers functional tissue architecture.bioRxiv : the preprint server for biology · 2026Article
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- Bidirectional interaction between protocadherin 8 and the transcription factor Dbx1 regulates cerebral cortex development.Development (Cambridge, England) · 2026Article
- Neocortical neurogenesis: a proneural gene perspective.The FEBS journal · 2025Review
- Tracing Early Migratory Neurons in the Developing Nose Using Contactin-2 (Cntn2) CreERT2.Genesis (New York, N.Y. : 2000) · 2025Article
- Genetic Effects of ITPK1 Polymorphisms on the Risk of Neural Tube Defects: a Population-Based Study.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- Identity, lineage and fates of a temporally distinct progenitor population in the embryonic olfactory epithelium.Developmental biology · 2023Article
- A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus.eLife · 2023Article
- EmAtlas: a comprehensive atlas for exploring spatiotemporal activation in mammalian embryogenesis.Nucleic acids research · 2023Article
- Nutrient sensitive proteinLife science alliance · 2022Article
- SHH and Notch regulate SOX9+ progenitors to govern arcuate POMC neurogenesis.Frontiers in neuroscience · 2022Article
- GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.Development (Cambridge, England) · 2021Article
- Epigenetics Is Implicated in the Basis of Gender Incongruence: An Epigenome-Wide Association Analysis.Frontiers in neuroscience · 2021Article
- The Role of Neurod Genes in Brain Development, Function, and Disease.Frontiers in molecular neuroscience · 2021Article
- Ldb1- and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in the retina.Development (Cambridge, England) · 2018Article
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5 authors.
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Abstract
backgroundNeurons arise in very specific regions of the neural tube, controlled by components of the Notch signalling pathway, proneural genes, and other bHLH transcription factors. How these specific neuronal areas in the brain are generated during development is just beginning to be elucidated. Notably, the critical role of proneural genes during differentiation of the neuronal populations that give rise to the early axon scaffold in the developing brain is not understood. The regulation of their downstream effectors remains poorly defined.
resultsThis study provides the first overview of the spatiotemporal expression of proneural genes in the neuronal populations of the early axon scaffold in both chick and mouse. Overexpression studies and mutant mice have identified a number of specific neuronal genes that are targets of proneural transcription factors in these neuronal populations.
conclusionTogether, these results improve our understanding of the molecular mechanisms involved in differentiation of the first neuronal populations in the brain.
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