ArticleNature structural & molecular biology2016
Elements of biological oscillations in time and space.
Article in Nature structural & molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Modified frequency-based sensitivity analysis for oscillatory system models.Journal of pharmacokinetics and pharmacodynamics · 2026Article
- Biomolecular condensates can function as inherent catalysts.Molecular cell · 2026Article
- Self-regulating and self-oscillating metal-organic framework hybrid plasmonic metasurfaces.Nature communications · 2025Article
- Flexible modulation of hybrid feedback loops in competitive biological oscillators.NPJ systems biology and applications · 2025Article
- Optimization of experimental designs for biological rhythm discovery.PLoS computational biology · 2025Article
- Experimentally Guided Iterative Parameter Estimation for Predictive Chemical Oscillator Models.Angewandte Chemie (International ed. in English) · 2025Article
- Condenzymes: Biomolecular condensates with inherent catalytic activities.bioRxiv : the preprint server for biology · 2025Article
- Arp2/3-dependent endocytosis ensures Cdc42 oscillations by removing Pak1-mediated negative feedback.The Journal of cell biology · 2024Article
- An oscillating reaction network with an exact closed form solution in the time domain.BMC bioinformatics · 2023Article
- The Arp2/3 complex promotes periodic removal of Pak1-mediated negative feedback to facilitate anticorrelated Cdc42 oscillations.bioRxiv : the preprint server for biology · 2023Article
- An improved rhythmicity analysis method using Gaussian Processes detects cell-density dependent circadian oscillations in stem cells.Bioinformatics (Oxford, England) · 2023Article
- Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level.Open biology · 2023Review
- An improved rhythmicity analysis method using Gaussian Processes detects cell-density dependent circadian oscillations in stem cells.bioRxiv : the preprint server for biology · 2023Article
- Light-Programmed Bistate Colloidal Actuation Based on Photothermal Active Plasmonic Substrate.Research (Washington, D.C.) · 2023Article
- Temporal control of the integrated stress response by a stochastic molecular switch.Science advances · 2022Article
- A variable refractory period increases collective performance in noisy environments.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Neural Synchrony and Network Dynamics in Social Interaction: A Hyper-Brain Cell Assembly Hypothesis.Frontiers in human neuroscience · 2022Article
- Origins of human disease: the chrono-epigenetic perspective.Nature reviews. Genetics · 2021Review
- CRISPR-based gene expression control for synthetic gene circuits.Biochemical Society transactions · 2020Review
- Misuse of the Michaelis-Menten rate law for protein interaction networks and its remedy.PLoS computational biology · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oscillations in time and space are ubiquitous in nature and play critical roles in dynamic cellular processes. Although the molecular mechanisms underlying the generation of the dynamics are diverse, several distinct regulatory elements have been recognized as being critical in producing and modulating oscillatory dynamics. These include negative and positive feedback, time delay, nonlinearity in regulation, and random fluctuations ('noise'). Here we discuss the specific roles of these five elements in promoting or attenuating oscillatory dynamics, by drawing on insights from quantitative analyses of natural or synthetic biological networks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.