ArticleMolecular psychiatry2017
Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.
Article in Molecular psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 9 of them syntheses that pooled it.
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Who cites it
50 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Shared genetic architecture of gray matter deficits in schizophrenia and bipolar disorder: evidence from structural neuroimaging-genetic analyses.Psychological medicine · 2026Pooled it
- Gene-level analysis reveals the genetic aetiology and therapeutic targets of schizophrenia.Nature human behaviour · 2025Pooled it
- Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia.Molecular psychiatry · 2024Pooled it
- Involvement of the long intergenic non-coding RNA LINC00461 in schizophrenia.BMC psychiatry · 2022Pooled it
- Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia.BMC medicine · 2021Pooled it
- A genome-wide association study reveals a substantial genetic basis underlying the Ebbinghaus illusion.Journal of human genetics · 2021Pooled it
- Multi-trait analysis for genome-wide association study of five psychiatric disorders.Translational psychiatry · 2020Pooled it
- Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations.Translational psychiatry · 2018Pooled it
- Pooled it
- Calcium signaling pathway implicates a shared genetic basis between psychiatric and cardiovascular diseases.Translational psychiatry · 2026Article
- SNP-based prediction of schizophrenia using machine learning.Bioinformatics advances · 2026Article
- Metabolic syndrome in patients with schizophrenia: Underlying mechanisms and therapeutic approaches (Review).Molecular medicine reports · 2025Review
- Genetic implication of GABAFrontiers in pharmacology · 2025Review
- Identification of Schizophrenia Susceptibility Loci in the Urban Taiwanese Population.Medicina (Kaunas, Lithuania) · 2024Article
- Normative modelling of molecular-based functional circuits captures clinical heterogeneity transdiagnostically in psychiatric patients.Communications biology · 2024Article
- Asian-European differentiation of schizophrenia-associated genes driven by admixture and natural selection.iScience · 2024Article
- Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice.BMC medicine · 2023Article
- Proteome-wide Mendelian randomization reveals the causal effects of immune-related plasma proteins on psychiatric disorders.Human genetics · 2023Article
- Genetic regulatory and biological implications of the 10q24.32 schizophrenia risk locus.Brain : a journal of neurology · 2023Article
- Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity.Thyroid : official journal of the American Thyroid Association · 2023Article
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32 authors.
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Abstract
Many schizophrenia susceptibility loci have been identified through genome-wide association studies (GWASs) in European populations. However, until recently, schizophrenia GWASs in non-European populations were limited to small sample sizes and have yielded few loci associated with schizophrenia. To identify genetic risk variations for schizophrenia in the Han Chinese population, we performed a two-stage GWAS of schizophrenia comprising 4384 cases and 5770 controls, followed by independent replications of 13 single-nucleotide polymorphisms in an additional 4339 schizophrenia cases and 7043 controls of Han Chinese ancestry. Furthermore, we conducted additional analyses based on the results in the discovery stage. The combined analysis confirmed evidence of genome-wide significant associations in the Han Chinese population for three loci, at 2p16.1 (rs1051061, in an exon of VRK2, P=1.14 × 10
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