ArticleCancer biology & therapy2017
Abscopal regression following SABR for non-small-cell-lung cancer: A case report.
Article in Cancer biology & therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-targeted effects of stereotactic radiotherapy: a review of the evidence coming from the clinical field.Exploration of targeted anti-tumor therapy · 2025Pooled it
- Regression of a Non-Irradiated Lung Adenocarcinoma During Glioblastoma-Directed Chemoradiotherapy: A Case Report.Current oncology (Toronto, Ont.) · 2026Article
- Abscopal effect induced by conventional fractionated radiotherapy following anti-PD-1 immunotherapy in pulmonary metastatic thymic squamous cell carcinoma: a case report and literature review.Frontiers in immunology · 2026Review
- Encountering the unicorn - abscopal effect after fractionated stereotactic radiosurgery for brain metastasis in renal cell carcinoma: a case report and review of the literature.Ecancermedicalscience · 2025Article
- Combination Immunotherapy With Radiotherapy in Non-Small Cell Lung Cancer: A Review of Evidence.Cancer medicine · 2024Review
- Abscopal effect-induced spontaneous regression of distant metastases in malignant mesenchymal tumor: a case report.Frontiers in oncology · 2024Article
- Combination therapy with hydrogen peroxide and irradiation promotes an abscopal effect in mouse models.Cancer science · 2023Article
- Abscopal Effect on Bone Metastases from Solid Tumors: A Systematic Review and Retrospective Analysis of Challenge within a Challenge.Biomedicines · 2023Article
- Abscopal effect in the radio and immunotherapy.Radiation oncology journal · 2021Article
- Abscopal Effects in Metastatic Cancer: Is a Predictive Approach Possible to Improve Individual Outcomes?Journal of clinical medicine · 2021Review
- TP53 drives abscopal effect by secretion of senescence-associated molecular signals in non-small cell lung cancer.Journal of experimental & clinical cancer research : CR · 2021Article
- Abscopal effect of radiation on multiple lung metastases of lung adenocarcinoma: a case report.BMC cancer · 2019Article
- Abscopal Effect of Radiotherapy in the Immunotherapy Era: Systematic Review of Reported Cases.Cureus · 2019Review
- Time to abandon single-site irradiation for inducing abscopal effects.Nature reviews. Clinical oncology · 2019Review
- Outcomes of Stage III NSCLC with occult primary vs. known primary lesions.Lung cancer (Amsterdam, Netherlands) · 2019Article
- From Whole-Brain Radiotherapy to Immunotherapy: A Multidisciplinary Approach for Patients with Brain Metastases from NSCLC.Journal of oncology · 2019Review
- Article
- Abscopal effect following radiation monotherapy in breast cancer: A case report.Molecular and clinical oncology · 2018Article
- The current state of oligometastatic and oligoprogressive non-small cell lung cancer.Journal of thoracic disease · 2018Review
- Report of an abscopal effect induced by stereotactic body radiotherapy and nivolumab in a patient with metastatic non-small cell lung cancer.Radiation oncology (London, England) · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Out-of-field tumor response, which is also called abscopal effect, bystander effect, or non-target effect, can be regarded as localized irradiation induced systemic antitumorigenic effects, indicating shrinkage of a tumor distant from the irradiated site. Although abscopal effect has been documented in several tumor types, it is a very rare phenomenon which is clinically reported in non-small-cell-lung carcinoma (NSCLC). Herein, we present a rare case of patient with NSCLC with 2 lesions in the upper lobe of left lung who, after receiving stereotactic ablative radiation therapy (SABR) to one of the tumors, had an apparent spontaneous regression of the other mass in the lung, suggestive of a radiation-induced abscopal effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.