Evidence map›Paper›PMID 27922192›Full record

ArticleJournal of cellular biochemistry2017

Evidence for Pipecolate Oxidase in Mediating Protection Against Hydrogen Peroxide Stress.

Sathish Kumar Natarajan, Ezhumalai Muthukrishnan, Oleh Khalimonchuk, Justin L Mott, Donald F Becker

Abstract read
In one paragraph

Article in Journal of cellular biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

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  19. mSphere · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sathish Kumar NatarajanDepartment of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.
Ezhumalai MuthukrishnanDepartment of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, 68583.
Oleh KhalimonchukDepartment of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.
Justin L MottDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska, 68198.
Donald F BeckerDepartment of Biochemistry and Redox Biology Center, University of Nebraska-Lincoln, Lincoln, Nebraska, 68588.
University of Nebraska–Lincoln · USUniversity of Nebraska Medical Center · US

Funding

The role of stress in the fetal origin of obesity and metabolic dysfunctionP20GM104320 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI ZEMPLENI, JANOS · 2014 to 2024
$24.9M
Research Pilot Project ProgramP30GM106397 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI JOHNSON, KEITH R · 2013 to 2017
$4.9M
Redox Biology CenterP30GM103335 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2012 to 2016
$4.3M
Role of Proline in Redox Homeostasis and ApoptosisR01GM079393 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI BECKER, DONALD F · 2008 to 2011
$1.1M
NIGMS NIH HHS P20 GM104320NIGMS NIH HHS P30 GM103335NIGMS NIH HHS P30 GM106397NIGMS NIH HHS R01 GM079393
6 · The paper itself

Abstract

Pipecolate, an intermediate of the lysine catabolic pathway, is oxidized to Δ

Indexed as

Cell SurvivalForkhead Box Protein O3Glucosephosphate DehydrogenaseHEK293 CellsHumansHydrogen PeroxideNADPOxidative StressOxidoreductases Acting on CH-NH Group DonorsPentose Phosphate PathwayPipecolic AcidsProto-Oncogene Proteins c-aktRNA, Small InterferingSarcosine OxidaseSignal TransductionTOR Serine-Threonine KinasesForkhead Box Protein O3Glucosephosphate DehydrogenaseHydrogen PeroxideL-pipecolate dehydrogenaseMTOR protein, humanNADPOxidoreductases Acting on CH-NH Group Donorspipecolic acidPipecolic AcidsPIPOX protein, humanProto-Oncogene Proteins c-aktRNA, Small InterferingSarcosine OxidaseTOR Serine-Threonine KinasesAMINO ACID METABOLISMMITOCHONDRIAOXIDATIVE STRESSPIPECOLATEPIPECOLATE OXIDASE

Identifiers

PMID27922192
PMCPMC5413420
OpenAlexW2560697782

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.