ArticleScientific reports2016
De Novo transcriptome characterization of Dracaena cambodiana and analysis of genes involved in flavonoid accumulation during formation of dragon's blood.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Genome-wide identification of the DFR gene family in Dracaena cambodiana and its expression analysis under wound stress.BMC plant biology · 2026Article
- Study on differences in flavonoid synthesis inFrontiers in plant science · 2026Article
- Identification of chalcone isomerase gene family inFrontiers in plant science · 2025Article
- Spatiotemporal composition and diversity of endophyte communities inFrontiers in microbiology · 2025Article
- Chromosome-level and haplotype-resolved genome assembly of Dracaena cambodiana (Asparagaceae).Scientific data · 2024Article
- Screening and validation of reference genes in Dracaena cochinchinensis using quantitative real-time PCR.Scientific reports · 2024Article
- Transcriptomics and Metabolomics Analyses Reveal Defensive Responses and Flavonoid Biosynthesis ofMolecules (Basel, Switzerland) · 2022Article
- The Transcriptome Profiling of Flavonoids and Bibenzyls Reveals Medicinal Importance of Rare OrchidFrontiers in plant science · 2022Article
- Characterization of Flavonoids and Transcripts Involved in Their Biosynthesis in Different Organs ofMetabolites · 2021Article
- Comparative transcriptome analysis of Alpinia oxyphylla Miq. reveals tissue-specific expression of flavonoid biosynthesis genes.BMC genomic data · 2021Article
- Transcriptomic Analyses Shed Light on Critical Genes Associated with Bibenzyl Biosynthesis inPlants (Basel, Switzerland) · 2021Article
- Identification and Characterization of Chalcone Isomerase Genes Involved in Flavonoid Production inFrontiers in plant science · 2021Article
- Comparative transcriptome among Euscaphis konishii Hayata tissues and analysis of genes involved in flavonoid biosynthesis and accumulation.BMC genomics · 2019Article
- The Research Progress of Chalcone Isomerase (CHI) in Plants.Molecular biotechnology · 2019Review
- Identification, characterization and expression analysis of genes involved in steroidal saponin biosynthesis in Dracaena cambodiana.Journal of plant research · 2018Article
- Transcriptome Analysis Reveals genes involved in flavonoid biosynthesis and accumulation in Dendrobium catenatum From Different Locations.Scientific reports · 2018Article
- Article
- Regulation of stilbene biosynthesis in plants.Planta · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dragon's blood is a red resin mainly extracted from Dracaena plants, and has been widely used as a traditional medicine in East and Southeast Asia. The major components of dragon's blood are flavonoids. Owing to a lack of Dracaena plants genomic information, the flavonoids biosynthesis and regulation in Dracaena plants remain unknown. In this study, three cDNA libraries were constructed from the stems of D. cambodiana after injecting the inducer. Approximately 266.57 million raw sequencing reads were de novo assembled into 198,204 unigenes, of which 34,873 unique sequences were annotated in public protein databases. Many candidate genes involved in flavonoid accumulation were identified. Differential expression analysis identified 20 genes involved in flavonoid biosynthesis, 27 unigenes involved in flavonoid modification and 68 genes involved in flavonoid transport that were up-regulated in the stems of D. cambodiana after injecting the inducer, consistent with the accumulation of flavonoids. Furthermore, we have revealed the differential expression of transcripts encoding for transcription factors (MYB, bHLH and WD40) involved in flavonoid metabolism. These de novo transcriptome data sets provide insights on pathways and molecular regulation of flavonoid biosynthesis and transport, and improve our understanding of molecular mechanisms of dragon's blood formation in D. cambodiana.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.