Chemically induced oxidative stress affects ASH neuronal function and behavior in C. elegans.

Eleni Gourgou, Nikos Chronis

Open access · goldAbstract read

In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it

0cells of the map it votes in

5citing papers in PubMed

1.0field-weighted citation impact, top 25% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

High-throughput behavioural phenotyping of 25 C. elegans disease models including patient-specific mutations.BMC biology · 2025
Article
Distinct mechanisms underlie H2O2 sensing in C. elegans head and tail.PloS one · 2022
Article
Left-right asymmetry in oxidative stress sensing neurons inmicroPublication biology · 2022
Article
Serotonin Disinhibits aThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
Article
A mathematical and computational model of the calcium dynamics in Caenorhabditis elegans ASH sensory neuron.PloS one · 2018
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eleni GourgouDepartment of Mechanical Engineering, University of Michigan, 2350 Hayward Str., Ann Arbor, MI, 48109, USA.

Nikos ChronisDepartment of Mechanical Engineering, University of Michigan, 2350 Hayward Str., Ann Arbor, MI, 48109, USA.

University of Michigan–Ann Arbor · US

Funding

A Biochip For Point-Of-Care HIV/AIDS Diagnosis in the Developing WorldDP2OD006458 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHRONIS, NIKOLAOS · 2009 to 2009

$2.3M

NIH HHS DP2 OD006458

6 · The paper itself

Abstract

Oxidative stress (OS) impact on a single neuron's function in vivo remains obscure. Using C. elegans as a model organism, we report the effect of paraquat (PQ)-induced OS on wild type worms on the function of the ASH polymodal neuron. By calcium (Ca

Indexed as

AnimalsBehavior, AnimalCaenorhabditis elegansCaenorhabditis elegans ProteinsCalciumLocomotionNeuronsOxidative StressParaquatCaenorhabditis elegans ProteinsCalciumParaquat

Identifiers

PMID27922032

DOI10.1038/srep38147

PMCPMC5138595

OpenAlexW2560247106

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.