ArticleJournal of Zhejiang University. Science. B
Antioxidant and antidiabetic properties of tartary buckwheat rice flavonoids after in vitro digestion.
Article in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 58 citations in OpenAlex.
- Comparative analysis of key phytochemicals and biological activities of Tartary buckwheat and Flos Sophorae Immaturus.Scientific reports · 2025Article
- Protective Effects of aMetabolites · 2024Article
- A Recent Advance on Phytochemicals, Nutraceutical and Pharmacological Activities of Buckwheat.Combinatorial chemistry & high throughput screening · 2024Review
- The Optimization of Assay Conditions and Characterization of the Succinic Semialdehyde Dehydrogenase Enzyme of Germinated Tartary Buckwheat.Foods (Basel, Switzerland) · 2023Article
- Dietary Phenolic Compounds: Their Health Benefits and Association with the Gut Microbiota.Antioxidants (Basel, Switzerland) · 2023Review
- Application of natural compounds in the treatment and prevention of prediabetes.Frontiers in nutrition · 2023Review
- A review: The nutrition components, active substances and flavonoid accumulation of Tartary buckwheat sprouts and innovative physical technology for seeds germinating.Frontiers in nutrition · 2023Review
- Agronomic and metabolomics analysis of rice-Tartary buckwheat (Fagopyrum tataricum Gaertn) bred by hybridization.Scientific reports · 2022Article
- Metabolism of Phenolics ofFoods (Basel, Switzerland) · 2021Article
- Edible Plant Sprouts: Health Benefits, Trends, and Opportunities for Novel Exploration.Nutrients · 2021Review
- Impact of In Vitro Gastrointestinal Digestion on the Bioaccessibility of Phytochemical Compounds from Eight Fruit Juices.Molecules (Basel, Switzerland) · 2021Article
- Spinosin Inhibits AβBiomolecules & therapeutics · 2020Article
- Tartary buckwheat extract alleviates alcohol-induced acute and chronic liver injuries through the inhibition of oxidative stress and mitochondrial cell death pathway.American journal of translational research · 2020Article
- Effects of simulated digestion on the phenolic composition and antioxidant activity of different cultivars of lychee pericarp.BMC chemistry · 2019Article
- Pericarp and seed of litchi and longan fruits: constituent, extraction, bioactive activity, and potential utilization.Journal of Zhejiang University. Science. B · 2019Review
- Dietary Flavonoid Intakes Are Associated with Race but Not Income in an Urban Population.Nutrients · 2018Article
- Mulberry Fruit Extract Affords Protection against Ethyl Carbamate-Induced Cytotoxicity and Oxidative Stress.Oxidative medicine and cellular longevity · 2017Article
- Activation of anthrachamycin biosynthesis in Streptomyces chattanoogensis L10 by site-directed mutagenesis of rpoB.Journal of Zhejiang University. Science. BArticle
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress and diabetes have a tendency to alter protein, lipid, and DNA moieties. One of the strategic methods used to reduce diabetes-associated oxidative stress is to inhibit the carbohydrate-digesting enzymes, thereby decreasing gastrointestinal glucose production. Plant-derived natural antioxidant molecules are considered a therapeutic tool in the treatment of oxidative stress and diabetes. The objective of this study was to identify tartary buckwheat rice flavonoids and evaluate the effect of in vitro digestion on their antioxidant and antidiabetic properties. High performance liquid chromatography (HPLC) analysis indicated the presence of rutin as a major component and quercitrin as a minor component of both digested and non-digested flavonoids. Both extracts showed a significant antioxidant capacity, but digested flavonoids showed reduced activity compared to non-digested. There were some decreases of the antioxidant activities (2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt (ABTS), 2,2-diphenyl-1-picrylhydrazy (DPPH) radical, and ferric reducing antioxidant power (FRAP)) of digested tartary buckwheat rice flavonoids compared with non-digested. Flavonoids from both groups significantly inhibited reactive oxygen species (ROS) production and α-glucosidase activity. Both digested and non-digested flavonoids markedly increased glucose consumption and glycogen content in HepG2 cells. Tartary buckwheat rice flavonoids showed appreciable antioxidant and antidiabetic properties, even after digestion. Tartary buckwheat rice appears to be a promising functional food with potent antioxidant and antidiabetic properties.
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