Evidence map›Paper›PMID 27921303›Full record

ArticleClinical and experimental immunology2017

Eosinophils from eosinophilic oesophagitis patients have T cell suppressive capacity and express FOXP3.

C Lingblom, J Wallander, M Ingelsten, H Bergquist, M Bove, R Saalman, A Welin, C Wennerås

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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  15. Alternative Splicing of FOXP3-Virtue and Vice.Frontiers in immunology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

C LingblomDepartment of Infectious Diseases, Head and Neck Surgery, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
J WallanderDepartment of Infectious Diseases, Head and Neck Surgery, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
M IngelstenDepartment of Infectious Diseases, Head and Neck Surgery, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
H BergquistDepartment of ENT, Head and Neck Surgery, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
M BoveDepartment of ENT, Head and Neck Surgery, NÄL Hospital, Trollhättan, Sweden.
R SaalmanDepartment of Pediatrics, Institution of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
A WelinDepartment of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
C WenneråsDepartment of Infectious Diseases, Head and Neck Surgery, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
University of Gothenburg · SENorra Älvsborgs Länssjukhus · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic esophagitis (EoE) is an antigen-driven T cell-mediated chronic inflammatory disease where food and environmental antigens are thought to have a role. Human eosinophils express the immunoregulatory protein galectin-10 and have T cell suppressive capacity similar to regulatory T cells (T

Indexed as

AdolescentAdultAgedEosinophilic EsophagitisEosinophilsFemaleForkhead Transcription FactorsHumansInflammationLeukocyte CountMaleMiddle AgedT-Lymphocytes, RegulatoryYoung AdultForkhead Transcription FactorsFOXP3 protein, humaneosinophilic esophagitiseosinophilsFOXP3regulatory T cellssuppression

Identifiers

PMID27921303
PMCPMC5290232
OpenAlexW2550188758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.