Evidence map›Paper›PMID 27921211›Full record

ArticlePflugers Archiv : European journal of physiology2017

Helix O modulates voltage dependency of CLC-1.

Ju Yong Seong, Kotdaji Ha, Chansik Hong, Jongyun Myeong, Hyun-Ho Lim, Dongki Yang, Insuk So

Abstract read
PubMed Publisher
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ju Yong SeongDepartment of Physiology, Seoul National University, College of Medicine, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-799, Republic of Korea.
Kotdaji HaDepartment of Physiology, Seoul National University, College of Medicine, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-799, Republic of Korea.
Chansik HongDepartment of Physiology, Seoul National University, College of Medicine, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-799, Republic of Korea.
Jongyun MyeongDepartment of Physiology, Seoul National University, College of Medicine, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-799, Republic of Korea.
Hyun-Ho LimKorea Brain Research Institute (KBRI), Daegu, 41068, Republic of Korea.
Dongki YangDepartment of Physiology, College of Medicine, Gachon University, Incheon, 461-701, Republic of Korea.
Insuk SoDepartment of Physiology, Seoul National University, College of Medicine, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-799, Republic of Korea. insuk@snu.ac.kr.
Seoul National University · KRGachon University · KRKorea Brain Research Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chloride channel (CLC) family of proteins consists of channels and transporters that share similarities in architecture and play essential roles in physiological functions. Among the CLC family, CLC-1 channels have the representative homodimeric double-barreled structure carrying two gating processes. One is protopore gating that acts on each pore independently by glutamate residue (E

Indexed as

Cell LineChloride ChannelsGlutamic AcidHEK293 CellsHumansIon Channel GatingMuscle, SkeletalMutationProtein Structure, SecondaryChloride ChannelsCLC-1 channelGlutamic AcidCLC-1Helix OProtonVoltage-gated channel

Identifiers

PMID27921211
OpenAlexW2559768098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.