Evidence map›Paper›PMID 27921185›Full record

Trial reportClinical rheumatology2017

Hand bone loss in early rheumatoid arthritis during a methotrexate-based treat-to-target strategy with or without adalimumab-a substudy of the optimized treatment algorithm in early RA (OPERA) trial.

L M Ørnbjerg, M Østergaard, T Jensen, K Hørslev-Petersen, K Stengaard-Pedersen, P Junker, T Ellingsen, P Ahlquist, H Lindegaard, A Linauskas and 21 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Skeletal complications of rheumatoid arthritis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 12 institutions in 1 country.

L M ØrnbjergCopenhagen Center for Arthritis Research and the DANBIO registry, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark. lykke@oernbjerg.dk.
M ØstergaardCopenhagen Center for Arthritis Research and the DANBIO registry, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark.
T JensenDepartment of Endocrinology, Hvidovre Hospital, Copenhagen, Denmark.
K Hørslev-PetersenKing Christian X Hospital for Rheumatic Diseases, South Jutland Hospital, Gråsten, Denmark.
K Stengaard-PedersenDepartment of Rheumatology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
P JunkerDepartment of Rheumatology C, Odense University Hospital, Odense, Denmark.
T EllingsenDiagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.
P AhlquistDepartment of Medicine, Vejle Regional Hospital, Vejle, Denmark.
H LindegaardDepartment of Rheumatology C, Odense University Hospital, Odense, Denmark.
A LinauskasDepartment of Rheumatology, Vendsyssel Hospital, Hjørring, Denmark.
A SchlemmerDepartment of Rheumatology, Aalborg University Hospital, Aalborg, Denmark.
M Y DamDiagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.
I HansenDepartment of Rheumatology, Viborg Regional Hospital, Viborg, Denmark.
T LottenburgerDepartment of Medicine, Vejle Regional Hospital, Vejle, Denmark.
C G AmmitzbøllDepartment of Rheumatology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
A JørgensenDepartment of Rheumatology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.
S B KrintelCopenhagen Center for Arthritis Research and the DANBIO registry, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark.
J RaunKing Christian X Hospital for Rheumatic Diseases, South Jutland Hospital, Gråsten, Denmark.
M L HetlandCopenhagen Center for Arthritis Research and the DANBIO registry, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark.
OPERA Study Group
Ole SlotCopenhagen Center for Arthritis Research and the DANBIO registry, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark.
Lars Kjær NielsenDepartment of Rheumatology, Odense University Hospital, Svendborg, Denmark.
Henrik SkjødtCopenhagen Center for Arthritis Research and the DANBIO registry, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark.
Ole MajgaardDepartment of Rheumatology, Slagelse Hospital, Slagelse, Denmark.
Tove LorenzenDiagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.
Hans Christian HornDepartment of Medicine, Vejle Regional Hospital, Vejle, Denmark.
Marcin KowalskiDepartment of Rheumatology, Viborg Regional Hospital, Viborg, Denmark.
Inger Lauge JohansenDepartment of Rheumatology, Viborg Regional Hospital, Viborg, Denmark.
Peter Mosborg PedersenDepartment of Rheumatology, Randers Regional Hospital, Randers, Denmark.
Natalia ManiloDepartment of Rheumatology, Bispebjerg Hospital, Copenhagen, Denmark.
Henning BliddalDepartment of Rheumatology, Parker Institute, Frederiksberg Hospital, Copenhagen, Denmark.
Odense University Hospital · DKRegionshospitalet Viborg · DKUniversity of Copenhagen · DKAarhus University Hospital · DKRigshospitalet · DKAalborg University Hospital · DKFrederiksberg Hospital · DKVejle Sygehus · DKBispebjerg Hospital · DKHvidovre Hospital · DKRegionshospitalet Silkeborg · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to investigate 1-year hand bone loss (HBL

Indexed as

Absorptiometry, PhotonAdalimumabAdultAlgorithmsAntirheumatic AgentsArthritis, RheumatoidBone DensityBone Diseases, MetabolicDenmarkDisease ProgressionDouble-Blind MethodDrug Therapy, CombinationFemaleHand BonesHumansLinear ModelsAdalimumabAntirheumatic AgentsMethotrexateAdalimumabDigital X-ray radiogrammetryHand bone lossRheumatoid arthritis

Identifiers

PMID27921185
OpenAlexW2558901186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.