Evidence map›Paper›PMID 27921168›Full record

ArticleJournal of gastroenterology2017

The 2016 diagnostic criteria for primary sclerosing cholangitis.

Takahiro Nakazawa, Kenji Notohara, Susumu Tazuma, Atsushi Tanaka, Hiroyuki Isayama, Toshio Tsuyuguchi, Toshiyuki Mori, Hajime Takikawa

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. [Guidelines on the diagnosis and management of primary sclerosing cholangitis (2021)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Guideline
  2. Clinical practice guidelines for IgG4-related sclerosing cholangitis.Journal of hepato-biliary-pancreatic sciences · 2019
    Guideline
  3. Guideline
  4. Observational
  5. Review
  6. Contribution of Endoscopy in the Diagnosis and Treatment of Patients With Primary Sclerosing Cholangitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Article
  7. Endoscopic management of primary sclerosing cholangitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Review
  8. Article
  9. Observational
  10. Symptom-based portopulmonary hypertension screening questionnaire in Japanese patients with chronic liver disease.JGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
  11. Article
  12. Observational
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Takahiro NakazawaDepartment of Gastroenterology, Japanese Red Cross Nagoya Daini Hospital, 2-9 Myoken-cho Showa-ku, Nagoya, 466-8650, Japan. tnakazaw@nagoya2.jrc.or.jp.ORCID http://orcid.org/0000-0002-6321-5995
Kenji NotoharaDepartment of Anatomic Pathology, Kurashiki Central Hospital, Kurashiki, Japan.
Susumu TazumaDepartment of General Internal Medicine, Hiroshima University Hospital and Graduate School of Biomedical and Health Science, Hiroshima, Japan.
Atsushi TanakaDepartment of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Hiroyuki IsayamaDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Toshio TsuyuguchiDepartment of Gastroenterology and Nephrology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Toshiyuki MoriDepartment of Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Hajime TakikawaDepartment of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Teikyo University · JPChiba University · JPHiroshima University Hospital · JPJapanese Red Cross Nagoya Daini Hospital · JPKurashiki Central Hospital · JPKyorin University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown cause that is characterized pathologically by an inflammatory and fibrotic process centered on the epithelium, leading to diffuse biliary stenosis and increased wall thickness throughout the intra- and extra-hepatic biliary trees. A nationwide survey in Japan revealed several differences in the clinical aspects of PSC between Japan and Western countries. PSC was recently designated an intractable hepatobiliary disease in Japan. The aim of this study was to establish Japanese diagnostic criteria for PSC according to the current Japanese conditions.

methodsThe Intractable Hepato-Biliary Diseases Study Group in Japan of the Committee of Research on Measures for Intractable Diseases established a working group consisting of researchers specializing in PSC and proposed the 2016 Japanese diagnostic criteria for PSC.

resultsThe diagnostic criteria consisted of the major and minor items. Major items are directly related to bile duct changes based on biliary tract imaging and an increased alkaline phosphatase level. Minor items consist of an association with inflammatory bowel disease and liver histology.

conclusionThe diagnostic criteria for PSC are useful for general physicians in practice.

Indexed as

Alkaline PhosphataseCholangiopancreatography, Endoscopic RetrogradeCholangiopancreatography, Magnetic ResonanceCholangitis, SclerosingHumansInflammatory Bowel DiseasesJapanLiverAlkaline PhosphatasePrimary sclerosing cholangitisPSCSclerosing cholangitis

Identifiers

PMID27921168
OpenAlexW2559839124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.