Evidence map›Paper›PMID 27921141›Full record

ReviewUrolithiasis2017

Kidney stones diseases and glycaemic statuses: focus on the latest clinical evidences.

Leonardo Spatola, Claudio Angelini, Salvatore Badalamenti, Silvio Maringhini, Giovanni Gambaro

Abstract readReview
PubMed Publisher
In one paragraph

Review in Urolithiasis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Leonardo SpatolaDivision of Nephrology, Humanitas Clinical and Research Center, via Manzoni 56, 20089, Rozzano, MI, Italy. leonardo.spatola@humanitas.it.ORCID http://orcid.org/0000-0002-8883-4776
Claudio AngeliniDivision of Nephrology, Humanitas Clinical and Research Center, via Manzoni 56, 20089, Rozzano, MI, Italy.
Salvatore BadalamentiDivision of Nephrology, Humanitas Clinical and Research Center, via Manzoni 56, 20089, Rozzano, MI, Italy.
Silvio MaringhiniDivision of Paediatric Nephrology, Ospedale "G. Di Cristina", Piazza Porta Montalto 2, 90134, Palermo, PA, Italy.
Giovanni GambaroDivision of Nephrology, Policlinico Universitario "Agostino Gemelli", Largo Agostino Gemelli 8, 00168, Rome, RM, Italy.
Humanitas University · ITAgostino Gemelli University Polyclinic · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes and obesity are already recognized as potential risk factors for nephrolithiasis, especially for uric acid stones. Insulin resistance and hyperinsulinemia actively contribute to impaired ability to excrete an acid load and altered ammonium production, leading to a lower urinary pH compared to non-diabetic controls. All these electrolytic disorders play an important role in stone formation and aggregation, especially in uric acid stones. There are still missing points in scientific evidence if the increased risk in stone formation is already existing even in the prediabetic statuses (isolated impaired glucose tolerance, isolated impaired fasting glucose, and associated impaired glucose tolerance/impaired fasting glucose) as well as it is worth to consider the same level of risk. Urolithiasis is the most frequent urological cause of hospitalization in diabetic patients and its cost is usually higher compared to non-diabetic patients, but less is known in others altered glycaemic diseases. The aim of this review article is to focus on the association between stone formation and altered glycaemic statuses, beyond the already known link between nephrolithiasis and diabetes mellitus.

Indexed as

Diabetes MellitusHumansHydrogen-Ion ConcentrationKidney CalculiMetabolic SyndromeObesityPrevalenceRisk FactorsUric AcidUric AcidImpaired fasting glucoseInsulin resistanceKidney stone diseaseMetabolic syndromeUric acid stones

Identifiers

PMID27921141
OpenAlexW2560434922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.