Evidence map›Paper›PMID 27921078›Full record

ArticleData in brief2016

Data on genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice.

Andrew T Grainger, Michael B Jones, Jing Li, Mei-Hua Chen, Ani Manichaikul, Weibin Shi

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrew T GraingerDepartments of Biochemistry & Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA.
Michael B JonesRadiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
Jing LiRadiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
Mei-Hua ChenRadiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
Ani ManichaikulPublic Health Sciences, University of Virginia, Charlottesville, Virginia, USA.
Weibin ShiDepartments of Biochemistry & Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA; Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, USA.
University of Virginia · US

Funding

Genetic link between type 2 diabetes and atherosclerosisR01DK097120 · NIDDK · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2013 to 2016
$1.4M
H2 haplotype and atherosclerosisR21HL112281 · NHLBI · UNIVERSITY OF VIRGINIA · PI SHI, WEIBIN · 2012 to 2013
$414k
NHLBI NIH HHS R21 HL112281NIDDK NIH HHS R01 DK097120
6 · The paper itself

Abstract

The data presented here are related to the research article, entitled Genetic analysis of atherosclerosis identifies a major susceptibility locus in the major histocompatibility complex of mice, published in Atherosclerosis 2016;254:124 (A.T. Grainger, M.B. Jones, J. Li, M.H. Chen, A. Manichaikul, W. Shi, 2016) [1]. The supporting materials include original genotypic and phenotypic data obtained from 206 female F2 mice derived from an intercross between BALB and SMJ inbred mice. The F2 mice were fed 12 weeks of Western diet, starting at 6 weeks of age. Atherosclerotic lesion size in the aortic root of each mouse is the sum of the top 8 lesion areas. The data is provided in the format required for determining QTLs using two independent programs, J/QTL and PLINK.

Indexed as

AtherosclerosisMajor histocompatibility complexMiceQuantitative trait locus

Identifiers

PMID27921078
PMCPMC5126130
OpenAlexW2553835733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.